N
Nayan D. Bhattacharyya
Researcher at University of Sydney
Publications - 17
Citations - 241
Nayan D. Bhattacharyya is an academic researcher from University of Sydney. The author has contributed to research in topics: T cell & Tuberculosis vaccines. The author has an hindex of 4, co-authored 12 publications receiving 104 citations. Previous affiliations of Nayan D. Bhattacharyya include Centenary Institute.
Papers
More filters
Journal ArticleDOI
Regulation of T Helper Cell Fate by TCR Signal Strength.
TL;DR: The signaling cascades regulated by the strength of TCR stimulation are summarized and various mechanisms in which TCR signal strength controls T helper cell expansion and differentiation are discussed.
Journal ArticleDOI
Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation
Sebastian A. Stifter,Sebastian A. Stifter,Nayan D. Bhattacharyya,Roman Pillay,Manuela Flórido,James A. Triccas,James A. Triccas,Warwick J. Britton,Warwick J. Britton,Carl G. Feng,Carl G. Feng +10 more
TL;DR: The study demonstrates that IFN interplay links innate and adaptive anti-viral immunity to orchestrate tissue inflammation and reveals an additional level of complexity for IFN-dependent regulatory mechanisms that function to prevent excessive immunopathology while preserving anti-microbial functions.
Journal ArticleDOI
Mucosal delivery of a multistage subunit vaccine promotes development of lung-resident memory T cells and affords interleukin-17-dependent protection against pulmonary tuberculosis.
Claudio Counoupas,Kia C. Ferrell,Anneliese S. Ashhurst,Nayan D. Bhattacharyya,Gayathri Nagalingam,Erica L. Stewart,Erica L. Stewart,Carl G. Feng,Nikolai Petrovsky,Warwick J. Britton,Warwick J. Britton,James A. Triccas +11 more
TL;DR: The findings suggest that tuberculosis vaccines such as CysVac2/Advax that are capable of eliciting Th17 lung-resident memory T cells are promising candidates for progression to human trials.
A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection.
Claudio Counoupas,Matt D. Johansen,Alberto Ospina Stella,Duc H. Nguyen,Angela Ferguson,Anupriya Aggarwal,Nayan D. Bhattacharyya,Alice Grey,Owen Hutchings,K. Patel,Rezwan Siddiquee,Erica L. Stewart,Carl G. Feng,Nicole G. Hansbro,Umaimainthan Palendira,Megan Steain,Bernadette M. Saunders,Jason Low,Joel P. Mackay,Anthony D. Kelleher,Warwick J. Britton,Stuart Turville,Philip M. Hansbro,James A. Triccas +23 more
TL;DR: In this paper, the authors exploit the immunostimulatory properties of bacille Calmette-Guerin (BCG), the existing tuberculosis vaccine, to deliver a vaccination regimen with potent SARS-CoV-2-specific protective immunity.
Journal ArticleDOI
Visualizing the Selectivity and Dynamics of Interferon Signaling In Vivo
Sebastian A. Stifter,Nayan D. Bhattacharyya,Andrew J. Sawyer,Taylor A. Cootes,John Stambas,Sean Doyle,Lionel Feigenbaum,William E. Paul,Warwick J. Britton,Alan Sher,Carl G. Feng +10 more
TL;DR: It is suggested that time- and cell-type-dependent integration of distinct IFN signals govern the specificity and magnitude of IFN responses in vivo.