Neal G. Uren

TL;DR: In humans, basal myocardial blood flow remains constant regardless of the severity of coronary-artery stenosis, however, during hyperemia, flow progressively decreases when the degree of stenosis is about 40 percent or more and does not differ significantly from basal flow when stenosis was 80 percent or greater.

TL;DR: 18)F-NaF PET-CT is the first non-invasive imaging method to identify and localise ruptured and high-risk coronary plaque and is needed to establish whether this method can improve the management and treatment of patients with coronary artery disease.

TL;DR: Event-free survival after failed thrombolytic therapy was significantly higher with rescue PCI than with repeated thrombalysis or conservative treatment, and rescue PCI should be considered for patients in whom reperfusion fails to occur after thrombectomy.

TL;DR: After acute myocardial infarction, there is a severe vasodilator abnormality involving not only resistance vessels in infarctedMyocardium, but also those in myocardium perfused by normal coronary vessels, which may affect the extent of myocardian ischemia and necrosis after coronary occlusion.

TL;DR: The study indicates how, in a situation in which myocardial oxygen demand is raised–tachycardia for example, a degree of stenosis that was sufficient for basal oxygen supply needs may be unable to provide flow requirements under the new conditions of oxygen supply and demand, hence the need for careful evaluation of the limited clinical evidence that most of us have of myocardium function during management of the authors' cases.