Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes.

From molecules to crystal engineering: supramolecular isomerism and polymorphism in network solids.

Free radicals, metals and antioxidants in oxidative stress-induced cancer

https://users.cs.duke.edu/~brd/Teaching/Bio/asmb/current/Papers/Lit4Docking/Gold_dock.pdf

Development and validation of a genetic algorithm for flexible docking.

BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

“Bioinformatics” 특집을 내면서

Free Radical Lipid Peroxidation: Mechanisms and Analysis

The primary producs formed from the autoxidation of lipids can be understood based upon a mechanism that involves five different reaction types. These reactions are: reaction of a carbon radical and molecular oxygen, atom transfer of a hydrogen from substrate to the chain carrying peroxyl, fragmentation of the chain carrying peroxyl to give oxygen and a carbon radical, rearrangement of the peroxyl, and cyclization of the peroxyl. The mechanisms of these primary reaction steps has been the focus of extensive research over the past fifty years, and the current level of understanding of these transformations is the subject of this review.

Ned A. Porter

Papers

Free Radical Lipid Peroxidation: Mechanisms and Analysis

Mechanisms of free radical oxidation of unsaturated lipids

Stereochemistry of Radical Reactions

Mechanisms for the autoxidation of polyunsaturated lipids

Acyclic stereochemical control in free-radical reactions