Nicholas A. Bokulich

TL;DR: QIIME 2 development was primarily funded by NSF Awards 1565100 to J.G.C. and R.K.P. and partial support was also provided by the following: grants NIH U54CA143925 and U54MD012388.

TL;DR: It is demonstrated that high-quality read length and abundance are the primary factors differentiating correct from erroneous reads produced by Illumina GAIIx, HiSeq and MiSeq instruments.

TL;DR: The results illustrate the importance of parameter tuning for optimizing classifier performance, and the recommendations regarding parameter choices for these classifiers under a range of standard operating conditions are made.

TL;DR: A meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project is presented, creating both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth’s microbial diversity.

TL;DR: It is shown that antibiotics, cesarean section, and infant formula alter patterns of microbial acquisition and succession during the first 2 years of childhood, which illustrates the complexity of early-life microbiome development and its sensitivity to perturbation.