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Nicholas A. Peppas
Researcher at University of Texas at Austin
Publications - 840
Citations - 101193
Nicholas A. Peppas is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Self-healing hydrogels & Polymer. The author has an hindex of 141, co-authored 825 publications receiving 90533 citations. Previous affiliations of Nicholas A. Peppas include National Technical University & University of Texas System.
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Mechanisms of solute release from porous hydrophilic polymers
TL;DR: In this article, the role of dynamic swelling and the dissolution of the polymer matrix on the release mechanism was discussed, as well as the effect of the tracer/excipient ratio on the poly(vinyl alcohol) release profile.
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Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology†
TL;DR: This work highlights recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for biomedical and biological applications and shows how such systems' intelligent behavior can be used in sensors, microarrays, and imaging.
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A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
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Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
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A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
TL;DR: In this paper, a simple exponential relation Mt/M∞ = ktn is introduced to describe the general solute release behavior of controlled release polymeric devices, where Mt is the fractional release, t is the release time, k is a constant, and n is the diffusional exponent characteristic of the release mechanism.