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Nicholas A. Peppas
Researcher at University of Texas at Austin
Publications - 840
Citations - 101193
Nicholas A. Peppas is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Self-healing hydrogels & Polymer. The author has an hindex of 141, co-authored 825 publications receiving 90533 citations. Previous affiliations of Nicholas A. Peppas include National Technical University & University of Texas System.
Papers
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Journal ArticleDOI
Multi-responsive hydrogels for drug delivery and tissue engineering applications
TL;DR: This article encompasses recent developments and challenges regarding supramolecular, layer-by-layer assembled and covalently cross-linked multi-responsive hydrogel networks and their application to drug delivery and tissue engineering.
Book ChapterDOI
Classes of Materials Used in Medicine
H. Alexander,John B. Brunski,Stuart L. Cooper,Larry L. Hench,Robert W. Hergenrother,Allan S. Hoffman,Joachim Kohn,Robert Langer,Nicholas A. Peppas,Buddy D. Ratner,Shalaby W. Shalaby,Susan A. Visser,Ioannis V. Yannas +12 more
TL;DR: This chapter explains various classes of materials used in medicine as they are applied to the selection of biomaterials and provides a table that compares some of the biomolecule immobilization techniques—physical and electrostatic adsorption, cross linking, entrapment, and covalent binding.
Journal ArticleDOI
The swollen polymer network hypothesis: Quantitative models of hydrogel swelling, stiffness, and solute transport
TL;DR: In this article, the authors present updates to a swollen polymer network hypothesis with a focus on hydrogel physical properties, including the connections between hydrogels structure, swelling behavior, mechanical properties, and transport properties.
Journal ArticleDOI
Designing Biomaterials To Direct Stem Cell Fate
TL;DR: This Perspective highlights important areas related to the design of biomaterials to control stem cell behavior, such as cell-responsive ligands, mechanical signals, and delivery of soluble factors.
Journal ArticleDOI
In vitro release behavior and stability of insulin in complexation hydrogels as oral drug delivery carriers.
Bumsang Kim,Nicholas A. Peppas +1 more
TL;DR: Hydrogels of P(MAA-co-MEG) prepared with an initial ratio of 1:4 MEG:MAA and P( MAA-g-EG) hydrogels containing PEG chains of molecular weights of 200 showed the greatest change in insulin release rate from acidic to basic pH solutions and the greatest protective effect for insulin in simulated GI tract conditions.