N
Nicholas A. Peppas
Researcher at University of Texas at Austin
Publications - 840
Citations - 101193
Nicholas A. Peppas is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Self-healing hydrogels & Polymer. The author has an hindex of 141, co-authored 825 publications receiving 90533 citations. Previous affiliations of Nicholas A. Peppas include National Technical University & University of Texas System.
Papers
More filters
Journal ArticleDOI
Label-Free Detection of Tear Biomarkers Using Hydrogel-Coated Gold Nanoshells in a Localized Surface Plasmon Resonance-Based Biosensor
TL;DR: The LSPR-based biosensor described herein has potential utility as an affordable screening tool for chronic dry eye and associated conditions and could be a useful, label-free signal transduction strategy for biosensing.
Journal ArticleDOI
A tumor-to-lymph procedure navigated versatile gel system for combinatorial therapy against tumor recurrence and metastasis.
Lin Qin,Jun Cao,Jun Cao,Kun Shao,Fan Tong,Zhihang Yang,Ting Lei,Yazhen Wang,Chuan Hu,Channakeshava Sokke Umeshappa,Huile Gao,Nicholas A. Peppas +11 more
TL;DR: In this article, a combinatorial therapy based on a α-cyclodextrin (CD)-based gel system, DOX/ICG/CpG-P-ss-M/CD, fabricated by encapsulating doxorubicin (DOX) and the photothermal agent indocyanine green (ICG), exhibited heat-responsive release of DOX and vaccine-like nanoparticles, along with chemotherapy-and phototherapy-generated abundant tumor-specific antigen storage in situ.
Journal ArticleDOI
Determination of interaction parameter χ1, for poly(vinyl alcohol) and water in gels crosslinked from solutions
Journal ArticleDOI
Characterization of pH-responsive hydrogels of poly(itaconic acid-g-ethylene glycol) prepared by UV-initiated free radical polymerization as biomaterials for oral delivery of bioactive agents.
TL;DR: P pH-responsive complexation hydrogels of poly(itaconic acid) with poly(ethylene glycol) (PEG) grafts were synthesized for applications in oral drug delivery and swelling increased with increasing pH up to a pH of about 6, when no further carboxylic acid deprotonation occurred.
Journal ArticleDOI
Oral delivery of small RNA and DNA
TL;DR: This work analyzes recently developed oral delivery methods for short RNA and DNA segments and suggests that effective oral delivery platforms for oligonucleotides may result in improved patient comfort and compliance.