N
Nicholas A. Peppas
Researcher at University of Texas at Austin
Publications - 840
Citations - 101193
Nicholas A. Peppas is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: Self-healing hydrogels & Polymer. The author has an hindex of 141, co-authored 825 publications receiving 90533 citations. Previous affiliations of Nicholas A. Peppas include National Technical University & University of Texas System.
Papers
More filters
Journal ArticleDOI
Solute diffusion in swollen membranes: VI. A model for diffusion in heterogeneous media
TL;DR: In this article, a new model was derived to calculate the solute diffusion coefficient through heterogeneous membranes consisting of a crosslinked, swollen phase and an impermeable, crystalline phase.
Journal ArticleDOI
Complexation Hydrogels as Oral Delivery Vehicles of Therapeutic Antibodies: An in Vitro and ex Vivo Evaluation of Antibody Stability and Bioactivity.
TL;DR: P(MAA-g-EG) and P(M AA-co-NVP) hydrogels systems were optimized to achieve adequate swelling behavior, which translated into improved protein loading and release at neutral pH simulating the small intestine conditions, which makes them candidates for use as oral delivery systems for therapeutic antibodies.
Journal ArticleDOI
An inulin and doxorubicin conjugate for improving cancer therapy
TL;DR: A new conjugate composed of doxorubicin and inulin and evaluated its potential as a new therapeutic agent for cancer treatment, finding the synergistic effect of inulin conjugated toDoxorubsicin has allowed the same cytotoxic response to be maintained or improved at lower doses as compared to doxOrubic in this research.
Journal ArticleDOI
Transport of penetrants in the macromolecular structure of coals. i. anomalous transport in untreated and pyridine-extracted coals
Nicholas A. Peppas,Lucy M. Lucht +1 more
TL;DR: In this paper, the authors investigated the mechanisms of penetrant transport in coal sections and particles and observed anomalous (non-Fickian) and Case-II transport were observed in much the same way as with glassy polymers.
Journal ArticleDOI
α-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effect in melanoma
Vanessa Sainz,Vanessa Sainz,Vanessa Sainz,Liane I.F. Moura,Liane I.F. Moura,Carina Peres,Ana I. Matos,Ana S. Viana,Angela M. Wagner,Julia E. Vela Ramirez,Teresa S. Barata,Manuela Gaspar,Steve Brocchini,Mire Zloh,Nicholas A. Peppas,Ronit Satchi-Fainaro,Helena F. Florindo +16 more
TL;DR: Overall, the combined delivery of the NKT agonist with TLR ligands and melanoma antigens via this multivalent nano-vaccine displayed a synergistic anti-tumor immune-mediated efficacy in B16F10 melanoma mouse model.