Author
Nicolas Sbirrazzuoli
Other affiliations: University of Utah, University of Nice Sophia Antipolis, University of Alabama at Birmingham
Bio: Nicolas Sbirrazzuoli is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Differential scanning calorimetry & Crystallization. The author has an hindex of 47, co-authored 134 publications receiving 10434 citations. Previous affiliations of Nicolas Sbirrazzuoli include University of Utah & University of Nice Sophia Antipolis.
Papers published on a yearly basis
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TL;DR: In this article, the authors have developed recommendations for reliable evaluation of kinetic parameters (the activation energy, the preexponential factor, and the reaction model) from the data obtained by means of thermal analysis methods such as TGA, differential scanning calorimetry (DSC), and differential thermal analysis (DTA).
4,112 citations
TL;DR: Isoconversional analysis of polymer kinetics has been studied extensively over the past decade as discussed by the authors and has been applied to a wide range of applications, including thermal degradation, crosslinking, glass transition, and glass and melt crystallization.
Abstract: Summary: Isoconversional kinetic analysis involves evaluating a dependence of the effective activation energy on conversion or temperature and using this dependence for making kinetic predictions and for exploring the mechanisms of thermally stimulated processes. The paper discusses major results obtained by the authors in the area of the isoconversional analysis of polymer kinetics over the past decade. It provides a brief introduction to isoconversional methods and surveys the impact made by isoconversional analysis in several application areas that include kinetic predictions, thermal degradation, crosslinking (curing), glass transition, and glass and melt crystallization. It is concluded that isoconversional analysis has been used broadly and fruitfully because it presents a fortunate compromise between the single-step Arrhenius kinetic treatments and the prevalent occurrence of processes whose kinetics are multi-step and/or non-Arrhenius.
An isoconversional method applies the Arrhenius equation to a narrow temperature region, ΔT related to a given extent of conversion.
942 citations
TL;DR: In this paper, the authors present a set of recommendations for obtaining kinetic data that are adequate to the actual kinetics of various processes, including thermal decomposition of inorganic solids; thermal and thermo-oxidative degradation of polymers and organics; reactions of solids with gases; polymerization and crosslinking; crystallization of polymer and inorganics; hazardous processes.
890 citations
TL;DR: In this paper, an isoconversional kinetic analysis has been applied to nonisothermal DSC data on the cure of an epoxynovolac resin, revealing a dependence of the activation energy (Eα) on conversion (α).
Abstract: The isoconversional kinetic analysis has been applied to nonisothermal DSC data on the cure of an epoxynovolac resin. The process reveals a dependence of the activation energy (Eα) on conversion (α). The shape of the dependence has been interpreted in the terms of the reaction mechanisms. It has been found that the model dα/dt = (k1 + αmk2)(1 − α)n used for the kinetically controlled cure gives rise to the dependence of Eα on α similar to the experimentally found one. To completely describe the diffusion-controlled cure, the effect of both T and α on the change in diffusivity has been taken into account. The equation for the specific rate constant of diffusion, kD(T,α) = Do exp(−ED/RT + Kα), has been induced. Its use allows us to obtain a model dependence of Eα on α closely matching the experimental one. A technique of predicting isothermal cure from the sole dependence of Eα on α has been considered.
398 citations
TL;DR: The present recommendations provide guidance on kinetic analysis of multi-step processes as measured by thermal analysis methods such as thermogravimetry and differential scanning calorimetry.
395 citations
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TL;DR: In this article, the authors have developed recommendations for reliable evaluation of kinetic parameters (the activation energy, the preexponential factor, and the reaction model) from the data obtained by means of thermal analysis methods such as TGA, differential scanning calorimetry (DSC), and differential thermal analysis (DTA).
4,112 citations
TL;DR: Two nonviral gene delivery systems using either biodegradable poly(D,Llactide-co-glycolide) (PLG) nanoparticles or cell penetrating peptide (CPP) complexes have been designed and studied using A549 human lung epithelial cells.
Abstract: The development of nonviral vectors for safe and efficient gene delivery has been gaining considerable attention recently. An ideal nonviral vector must protect the gene against degradation by nuclease in the extracellular matrix, internalize the plasma membrane, escape from the endosomal compartment, unpackage the gene at some point and have no detrimental effects. In comparison to viruses, nonviral vectors are relatively easy to synthesize, less immunogenic, low in cost, and have no limitation in the size of a gene that can be delivered. Significant progress has been made in the basic science and applications of various nonviral gene delivery vectors; however, the majority of nonviral approaches are still inefficient and often toxic. To this end, two nonviral gene delivery systems using either biodegradable poly(D,Llactide-co-glycolide) (PLG) nanoparticles or cell penetrating peptide (CPP) complexes have been designed and studied using A549 human lung epithelial cells. PLG nanoparticles were optimized for gene delivery by varying particle surface chemistry using different coating materials that adsorb to the particle surface during formation. A variety of cationic coating materials were studied and compared to more conventional surfactants used for PLG nanoparticle fabrication. Nanoparticles (~200 nm) efficiently encapsulated plasmids encoding for luciferase (80-90%) and slowly released the same for two weeks. After a delay, moderate levels of gene expression appeared at day 5 for certain positively charged PLG particles and gene expression was maintained for at least two weeks. In contrast, gene expression mediated by polyethyleneimine (PEI) ended at day 5. PLG particles were also significantly less
2,189 citations
TL;DR: A broad review of the state-of-the-art biomass pyrolysis research can be found in this article, where three major components (cellulose, hemicellulose and lignin) are discussed in detail.
1,613 citations
TL;DR: In this paper, the model-free and model-fitting approaches have been applied to data for nonisothermal and isothermal thermal decompositions of HMX and ammonium dinitramide.
1,168 citations