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Nicole Pischon
Researcher at Charité
Publications - 37
Citations - 2250
Nicole Pischon is an academic researcher from Charité. The author has contributed to research in topics: Periodontitis & Lysyl oxidase. The author has an hindex of 20, co-authored 37 publications receiving 2064 citations. Previous affiliations of Nicole Pischon include Boston University & University of Birmingham.
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Journal ArticleDOI
Obesity, Inflammation, and Periodontal Disease
Nicole Pischon,N. Heng,Jean-Pierre Bernimoulin,Bernd-Michael Kleber,Stefan N. Willich,Tobias Pischon +5 more
TL;DR: The definition and assessment of obesity and of related chronic diseases and complications that may be important in the periodontist’s office are provided and adipose-tissue-derived hormones and cytokines that are involved in inflammatory processes and their relationship to periodontitis are discussed.
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Association Among Rheumatoid Arthritis, Oral Hygiene, and Periodontitis
Nicole Pischon,Tobias Pischon,J. Kröger,E. Gülmez,Bernd-Michael Kleber,Jean-Pierre Bernimoulin,Helga Landau,P.-G. Brinkmann,P. Schlattmann,Jan Zernicke,Frank Buttgereit,Jacqueline Detert +11 more
TL;DR: Only RA status and age remained significant predictors of periodontal disease in a stepwise logistic regression, including RA status, age, gender, education, smoking, alcohol consumption, and BMI.
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Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways.
Mani Alikhani,Zoubin Alikhani,Coy M. Boyd,Christine M. MacLellan,Markos Raptis,Rongkun Liu,Nicole Pischon,Philip C. Trackman,Louis C. Gerstenfeld,Dana T. Graves +9 more
TL;DR: The results indicate that advanced glycation end products, which accumulate in diabetic and aged individuals, may promote apoptosis of osteoblastic cells and contribute to deficient bone formation.
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The association between rheumatoid arthritis and periodontal disease
TL;DR: There are findings that support the hypothesis that oral infections play a role in RA pathogenesis and the association of PD in RA patients with seropositivity toward rheumatoid factor and the anti-cyclic citrullinated peptide antibody is discussed.
Journal ArticleDOI
The Propeptide Domain of Lysyl Oxidase Induces Phenotypic Reversion of Ras-transformed Cells
Amitha H. Palamakumbura,Sébastien Jeay,Ying Guo,Nicole Pischon,Pascal Sommer,Gail E. Sonenshein,Philip C. Trackman +6 more
TL;DR: It is reported, for the first time, that the lysyl oxidase propeptide, and not thelysyl oxidation enzyme, inhibits ras-dependent transformation as determined by effects on cell proliferation assays, growth in soft agar, and Akt-dependent induction of NF-κB activity.