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Niels K. Jerne
Researcher at Basel Institute for Immunology
Publications - 25
Citations - 9439
Niels K. Jerne is an academic researcher from Basel Institute for Immunology. The author has contributed to research in topics: Immune system & Antibody. The author has an hindex of 20, co-authored 24 publications receiving 9354 citations. Previous affiliations of Niels K. Jerne include California Institute of Technology & University of Pittsburgh.
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Journal ArticleDOI
Plaque Formation in Agar by Single Antibody-Producing Cells
Niels K. Jerne,Albert A. Nordin +1 more
TL;DR: Distinct plaques, each of which is due to the release of hemolysin by a single antibody-forming cell, are revealed by complement after incubation, in an agar layer, of a mixture of Sheep red cells and lymphoid cells from a rabbit immunized with sheep red cells.
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The somatic generation of immune recognition.
TL;DR: The present hypothesis proposes that the germ‐cells of an animal carry a set of v‐genes determining the combining sites of antibodies directed against a complete set of a certain class of histocompatibility antigens of the species to which this animal belongs.
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The natural-selection theory of antibody formation.
TL;DR: The theory formulated in the present paper, though highly speculative, attempts to provide a framework for the interpretation of the main features of antibody appearance in response to the injection of antigen into an animal.
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Idiotypic networks and other preconceived ideas.
TL;DR: “Mirrors would be well‐advised to think twice before reflecting images”.