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Nikesh A. Shah

Bio: Nikesh A. Shah is an academic researcher from Saurashtra University. The author has contributed to research in topics: Dielectric & Manganite. The author has an hindex of 21, co-authored 142 publications receiving 1401 citations.


Papers
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TL;DR: Results demonstrate that ZnO-NP could be developed as alternative therapeutics against A. baumannii, and the proposed mechanism of action of ZNO involves the production of reactive oxygen species, which elevates membrane lipid peroxidation that causes membrane leakage of reducing sugars, DNA, proteins, and reduces cell viability.
Abstract: Acinetobacter baumannii is a multi-drug resistant opportunistic pathogen, which causes respiratory and urinary tract infections. Its prevalence increases gradually in the clinical setup. Carbapenems (beta-lactam) are most effective antibiotics till now against A. baumannii, but the development of resistance against it may lead to high mortality. Therefore, it is of utmost importance to develop an alternative drug against A. baumannii. In the present study, we have synthesized ZnO nanoparticle (ZnO-NP) and characterized by X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy and UV-Visible spectroscopy. Prepared ZnO-NPs have the size of 30 nm and have different characteristics of ZnO-NPs. Growth kinetics and disk diffusion assay showed that ZnO-NP demonstrated good antibacterial activity against carbapenem resistant A. baumannii. We have also investigated the mechanism of action of ZnO-NPs on the carbapenem resistant strain of A. baumannii. The proposed mechanism of action of ZnO involves the production of reactive oxygen species, which elevates membrane lipid peroxidation that causes membrane leakage of reducing sugars, DNA, proteins, and reduces cell viability. These results demonstrate that ZnO-NP could be developed as alternative therapeutics against A. baumannii.

276 citations

Journal ArticleDOI
TL;DR: In this article, the effect of 200 MeV Ag+15 ion irradiation on LPMO manganite has been investigated and the results of the structural, microstructural, transport and magnetotransport properties of pristine and irradiated LPMI films (150-350 nm) have been discussed.

58 citations

Journal ArticleDOI
TL;DR: In this paper, structural, magnetic and transport studies on monovalent doped La1−xNaxMnO3 mixed valent manganites synthesized by conventional ceramic route are reported.

54 citations

Journal ArticleDOI
TL;DR: In this paper, the structural and micro-structural properties of sol-gel grown nanostructured La0.6Nd0.1Sr0.3MnO3 (LNSMO) manganites sintered and annealed at different temperatures (viz., 700, 800 and 900 °C).

53 citations

Journal ArticleDOI
TL;DR: In this article, the magnetic properties of phase-separated La 0.4 Dy 0.1 Ca 0.5 MnO 3 polycrystalline bulk sample have been investigated.

50 citations


Cited by
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08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

01 Jun 2005

3,154 citations

16 Mar 1993
TL;DR: Giant and isotropic magnetoresistance as huge as −53% was observed in magnetic manganese oxide La0.72Ca0.25MnOz films with an intrinsic antiferromagnetic spin structure as discussed by the authors.
Abstract: Giant and isotropic magnetoresistance as huge as −53% was observed in magnetic manganese oxide La0.72Ca0.25MnOz films with an intrinsic antiferromagnetic spin structure. We ascribe this magnetoresistance to spin‐dependent electron scattering due to spin canting of the manganese oxide.

924 citations

Journal ArticleDOI
TL;DR: A review of the general types of nanoparticles and their functionalization via covalent or noncovalent interactions using different methods is presented in this paper, which highlights the techniques used for the characterization of NPs and discusses their physical and chemical properties.
Abstract: Nanomaterials (NMs) are gaining significance in technological applications due to their tunable chemical, physical, and mechanical properties and enhanced performance when compared with their bulkier counterparts. This review presents a summary of the general types of NMs and provides an overview of the various synthesis methods of nanoparticles (NPs) and their functionalization via covalent or noncovalent interactions using different methods. It highlights the techniques used for the characterization of NPs and discusses their physical and chemical properties. Due to their unique properties, NMs have several applications and have become part of our daily lives. As a result, nanotoxicity research is gaining attention since some NPs are not easily degraded by the environment. Thus, this review also highlights research efforts into the fate, behavior, and toxicity of different classes of NMs in the environment.

548 citations