N
Nilesh J. Samani
Researcher at University of Leicester
Publications - 836
Citations - 127518
Nilesh J. Samani is an academic researcher from University of Leicester. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 149, co-authored 779 publications receiving 113545 citations. Previous affiliations of Nilesh J. Samani include University Hospitals of Leicester NHS Trust & Glenfield Hospital.
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Yun J. Sung,Thomas W. Winkler,Lisa de las Fuentes,Amy R. Bentley,Michael R. Brown,Aldi T. Kraja,Karen Schwander,Ioanna Ntalla,Xiuqing Guo,Nora Franceschini,Yingchang Lu,Ching-Yu Cheng,Xueling Sim,Dina Vojinovic,Jonathan Marten,Solomon K. Musani,Changwei Li,Mary F. Feitosa,Tuomas O. Kilpeläinen,Melissa A. Richard,Raymond Noordam,Stella Aslibekyan,Hugues Aschard,Traci M. Bartz,Rajkumar Dorajoo,Yongmei Liu,Alisa K. Manning,Tuomo Rankinen,Albert V. Smith,Salman M. Tajuddin,Bamidele O. Tayo,Helen R. Warren,Wei Zhao,Yanhua Zhou,Nana Matoba,Tamar Sofer,Maris Alver,Marzyeh Amini,Mathilde Boissel,Jin-Fang Chai,Xu Chen,Jasmin Divers,Ilaria Gandin,Chuan Gao,Franco Giulianini,Anuj Goel,Sarah E. Harris,Fernando Pires Hartwig,Andrea R. V. R. Horimoto,Fang-Chi Hsu,Anne U. Jackson,Mika Kähönen,Anuradhani Kasturiratne,Brigitte Kühnel,Karin Leander,Wen-Jane Lee,Keng-Hung Lin,Jian'an Luan,Colin A. McKenzie,He Meian,Christopher P. Nelson,Rainer Rauramaa,Nicole Schupf,Robert A. Scott,Wayne Huey-Herng Sheu,Alena Stančáková,Fumihiko Takeuchi,Peter J. van der Most,Tibor V. Varga,Heming Wang,Yajuan Wang,Erin B. Ware,Stefan Weiss,Wanqing Wen,Lisa R. Yanek,Weihua Zhang,Jing Hua Zhao,Saima Afaq,Tamuno Alfred,Najaf Amin,Dan E. Arking,Tin Aung,R. Graham Barr,Lawrence F. Bielak,Eric Boerwinkle,Erwin P. Bottinger,Peter S. Braund,Jennifer A. Brody,Ulrich Broeckel,Claudia P. Cabrera,Brian E. Cade,Yu Caizheng,Archie Campbell,Mickaël Canouil,Aravinda Chakravarti,Ganesh Chauhan,Kaare Christensen,Massimiliano Cocca,Francis S. Collins,John M. C. Connell,Renée de Mutsert,H. Janaka de Silva,Stéphanie Debette,Marcus Dörr,Qing Duan,Charles B. Eaton,Georg Ehret,Evangelos Evangelou,Jessica D. Faul,Virginia Fisher,Nita G. Forouhi,Oscar H. Franco,Yechiel Friedlander,He Gao,Bruna Gigante,Misa Graff,C. Charles Gu,Dongfeng Gu,Preeti Gupta,Saskia P. Hagenaars,Tamara B. Harris,Jiang He,Sami Heikkinen,Chew-Kiat Heng,Makoto Hirata,Albert Hofman,Barbara V. Howard,Steven C. Hunt,Marguerite R. Irvin,Yucheng Jia,Roby Joehanes,Anne E. Justice,Tomohiro Katsuya,Joel D. Kaufman,Nicola D. Kerrison,Chiea Chuen Khor,Woon-Puay Koh,Heikki A. Koistinen,Pirjo Komulainen,Charles Kooperberg,José Eduardo Krieger,Michiaki Kubo,Johanna Kuusisto,Carl D. Langefeld,Claudia Langenberg,Lenore J. Launer,Benjamin Lehne,Cora E. Lewis,Yize Li,Sing Hui Lim,Shiow Lin,Ching-Ti Liu,Jianjun Liu,Jingmin Liu,Kiang Liu,Y Liu,Marie Loh,Kurt Lohman,Jirong Long,Tin Louie,Reedik Mägi,Anubha Mahajan,Thomas Meitinger,Andres Metspalu,Lili Milani,Yukihide Momozawa,Andrew P. Morris,Thomas H. Mosley,Peter J. Munson,Alison D. Murray,Mike A. Nalls,Ubaydah Nasri,Jill M. Norris,Kari E. North,Adesola Ogunniyi,Sandosh Padmanabhan,Walter Palmas,Nicholette D. Palmer,James S. Pankow,Nancy L. Pedersen,Annette Peters,Patricia A. Peyser,Ozren Polasek,Olli T. Raitakari,Frida Renström,Treva Rice,Paul M. Ridker,Antonietta Robino,Jennifer G. Robinson,Lynda M. Rose,Igor Rudan,Charumathi Sabanayagam,Babatunde L. Salako,Kevin Sandow,Carsten Oliver Schmidt,Pamela J. Schreiner,William R. Scott,Sudha Seshadri,Peter S. Sever,Colleen M. Sitlani,Jennifer A. Smith,Harold Snieder,John M. Starr,Konstantin Strauch,Hua Tang,Kent D. Taylor,Yik Ying Teo,Yih Chung Tham,Andre G. Ultterlinden,Melanie Waldenberger,Lihua Wang,Ya X. Wang,Wen Bin Wei,Christine Williams,Gregory P. Wilson,Mary K. Wojczynski,Jie Yao,Jian-Min Yuan,Alan B. Zonderman,Diane M. Becker,Michael Boehnke,Donald W. Bowden,John C. Chambers,Yii-Der Ida Chen,Ulf de Faire,Ian J. Deary,Tõnu Esko,Martin Farrall,Terrence Forrester,Paul W. Franks,Barry I. Freedman,Philippe Froguel,Paolo Gasparini,Christian Gieger,Bernardo L. Horta,Yi-Jen Hung,Jost B. Jonas,Norihiro Kato,Jaspal S. Kooner,Markku Laakso,Terho Lehtimäki,Kae-Woei Liang,Patrik K. E. Magnusson,Anne B. Newman,Albertine J. Oldehinkel,Alexandre C. Pereira,Susan Redline,Rainer Rettig,Nilesh J. Samani,James F. Scott,Xiao-Ou Shu,Pim van der Harst,Lynne E. Wagenknecht,Nicholas J. Wareham,Hugh Watkins,David R. Weir,Ananda R. Wickremasinghe,Tangchun Wu,Wei Zheng,Yoichiro Kamatani,Cathy C. Laurie,Claude Bouchard,Richard S. Cooper,Michele K. Evans,Vilmundur Gudnason,Sharon L.R. Kardia,Stephen B. Kritchevsky,Daniel Levy,Jeffrey R. O'Connell,Bruce M. Psaty,Rob M. van Dam,Mario Sims,Donna K. Arnett,Dennis O. Mook-Kanamori,Tanika N. Kelly,Ervin R. Fox,Caroline Hayward,Myriam Fornage,Charles N. Rotimi,Michael A. Province,Cornelia M. van Duijn,E. Shyong Tai,Tien Yin Wong,Ruth J. F. Loos,Alexander P. Reiner,Jerome I. Rotter,Xiaofeng Zhu,Laura J. Bierut,W. James Gauderman,Mark J. Caulfield,Paul Elliott,Kenneth Rice,Patricia B. Munroe,Alanna C. Morrison,L. Adrienne Cupples,Dabeeru C. Rao,Daniel I. Chasman +296 more
TL;DR: In this article, the authors performed genome-wide association meta-analyses of systolic and diastolic BP incorporating gene-smoking interactions in 610,091 individuals.
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Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers
Kyle M. Walsh,Todd P. Whitehead,Adam J. de Smith,Ivan Smirnov,Minsun Park,Alyson A. Endicott,Stephen S. Francis,Veryan Codd,Veryan Codd,Nilesh J. Samani,Nilesh J. Samani,Catherine Metayer,Joseph L. Wiemels +12 more
TL;DR: Genetic predisposition to longer LTL is a newly identified risk factor for neuroblastoma and potentially for other cancers of childhood, and a weighted linear combination of the eight LTL-associated SNPs are observed.
Journal ArticleDOI
Posttraumatic stress disorder and not depression is associated with shorter leukocyte telomere length: findings from 3,000 participants in the population-based KORA F4 study.
Karl-Heinz Ladwig,Anne Catharina Brockhaus,Jens Baumert,Karoline Lukaschek,Rebecca T. Emeny,Johannes Kruse,Veryan Codd,Veryan Codd,S. Häfner,Eva Albrecht,Thomas Illig,Nilesh J. Samani,Nilesh J. Samani,H.-Erich Wichmann,Christian Gieger,Annette Peters +15 more
TL;DR: The dose-dependent variation in TL of subjects with partial and full PTSD exceeded the chronological age effect, and was equivalent to an estimated 5 years in partial and 10 years in full PTSD of premature aging.
Journal ArticleDOI
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension
Jordana T. Bell,Chris Wallace,Richard Dobson,Steven Wiltshire,Charles A. Mein,J Pembroke,Morris J. Brown,David Clayton,Nilesh J. Samani,Anna F. Dominiczak,John Webster,G. Mark Lathrop,John M. C. Connell,Patricia B. Munroe,Mark J. Caulfield,Martin Farrall +15 more
TL;DR: This approach has discovered novel loci for hypertension and offers a unique potential to use existing data to uncover novel regions involved in complex human diseases.
Journal ArticleDOI
Telomere length and psychological well-being in patients with chronic heart failure
Jardi Huzen,Pim van der Harst,Rudolf A. de Boer,Ivonne Lesman-Leegte,Adriaan A. Voors,Wiek H. van Gilst,Nilesh J. Samani,Tiny Jaarsma,Dirk J. van Veldhuisen +8 more
TL;DR: In this article, the authors evaluated the perceived mental health by the validated RAND-36 questionnaire and found that lower perceived mental wellbeing was associated with shorter leukocyte telomere length in patients with chronic heart failure.