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Nilesh J. Samani
Researcher at University of Leicester
Publications - 836
Citations - 127518
Nilesh J. Samani is an academic researcher from University of Leicester. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 149, co-authored 779 publications receiving 113545 citations. Previous affiliations of Nilesh J. Samani include University Hospitals of Leicester NHS Trust & Glenfield Hospital.
Papers
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Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking
Sarah H. Stephens,Sarah M. Hartz,Nicole R. Hoft,Nancy L. Saccone,Robin C. Corley,John K. Hewitt,Christian J. Hopfer,Naomi Breslau,Hilary Coon,Xiangning Chen,Francesca Ducci,Nicole Dueker,Nora Franceschini,Josef Frank,Younghun Han,Nadia N. Hansel,Chenhui Jiang,Tellervo Korhonen,Penelope A. Lind,Jason Z. Liu,Leo-Pekka Lyytikaeinen,Martha Michel,John R. Shaffer,Susan E. Short,Juzhong Sun,Alexander Teumer,John R. Thompson,Nicole Vogelzangs,Jacqueline M. Vink,Angela S. Wenzlaff,William Wheeler,Bao-Zhu Yang,Steven H. Aggen,Anthony J. Balmforth,Sebastian E. Baumeister,Terri H. Beaty,Daniel J. Benjamin,Andrew W. Bergen,Ulla Broms,David Cesarini,Nilanjan Chatterjee,Jingchun Chen,Yu-Ching Cheng,Sven Cichon,David Couper,Francesco Cucca,Danielle M. Dick,Tatiana Foroud,Helena Furberg,Ina Giegling,Nathan A. Gillespie,Fangyi Gu,Alistair S. Hall,Jenni Haellfors,Shizhong Han,Annette M. Hartmann,Kauko Heikkilae,Ian B. Hickie,Jouke-Jan Hottenga,Pekka Jousilahti,Marika Kaakinen,Mika Kaehoenen,Philipp Koellinger,Stephen Kittner,Bettina Konte,Maria-Teresa Landi,Tiina Laatikainen,Mark Leppert,Steven M. Levy,Rasika A. Mathias,Daniel W. McNeil,Sarah E. Medland,Grant W. Montgomery,Tanda Murray,Matthias Nauck,Kari E. North,Peter D. Paré,Michele L. Pergadia,Ingo Ruczinski,Veikko Salomaa,Jorma Viikari,Gonneke Willemsen,Kathleen C. Barnes,Eric Boerwinkle,Dorret I. Boomsma,Neil E. Caporaso,Howard J. Edenberg,Clyde Francks,Joel Gelernter,Hans Joergen Grabe,Hyman Hops,Marjo-Riitta Järvelin,Magnus Johannesson,Kenneth S. Kendler,Terho Lehtimaeki,Patrik K. E. Magnusson,Mary L. Marazita,Jonathan Marchini,Braxton D. Mitchell,Markus M. Noethen,Brenda W.J.H. Penninx,Olli T. Raitakari,Marcella Rietschel,Dan Rujescu,Nilesh J. Samani,Ann G. Schwartz,Sanjay Shete,Margaret R. Spitz,Gary E. Swan,Henry Voelzke,Juha Veijola,Qingyi Wei,Christopher I. Amos,Dale S. Cannon,Richard A. Grucza,Dorothy K. Hatsukami,Andrew Heath,Eric O. Johnson,Jaakko Kaprio,Pamela A. F. Madden,Nicholas G. Martin,Victoria L. Stevens,Robert B. Weiss,Peter Kraft,Laura J. Bierut,Marissa A. Ehringer +125 more
Journal ArticleDOI
Pathway Analysis Shows Association between FGFBP1 and Hypertension
Maciej Tomaszewski,Fadi J. Charchar,Christopher P. Nelson,Timothy A. Barnes,Matthew Denniff,Michael A. Kaiser,Radoslaw Debiec,Paraskevi Christofidou,Suzanne Rafelt,Pim van der Harst,William Y.S. Wang,William Y.S. Wang,Christine Maric,Ewa Zukowska-Szczechowska,Nilesh J. Samani +14 more
TL;DR: It is suggested that FGFBP1 associates with hypertension and that systematic analysis of signaling pathways can identify previously undescribed genetic associations.
Journal Article
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages
Yunlong Yang,Patrik Andersson,Kayoko Hosaka,Yin Zhang,Renhai Cao,Hideki Iwamoto,Xiaojuan Yang,Masaki Nakamura,Jing Wang,Rujie Zhuang,Hiromasa Morikawa,Harald Braun,Rudi Beyaert,Nilesh J. Samani,Susumu Nakae,Emily Hams,Steen Dissing,Padraic G. Fallon,Yihai Cao,Yuan Xue,Robert Langer +20 more
TL;DR: A mechanism of the interaction between perivascular cells and tumour-associated macrophages (TAMs) in promoting metastasis through the IL-33–ST2-dependent pathway in xenograft mouse models of cancer is reported.
Journal ArticleDOI
Coronary Artery Disease–Related Genetic Variant on Chromosome 10q11 Is Associated With Carotid Intima-Media Thickness and Atherosclerosis
Stefan Kiechl,Ross C. Laxton,Qingzhong Xiao,Jussi Hernesniemi,Olli T. Raitakari,Mika Kähönen,Bongani M. Mayosi,Bongani M. Mayosi,Antti Jula,Leena Moilanen,Johann Willeit,Hugh Watkins,Nilesh J. Samani,Terho Lehtimäki,Bernard Keavney,Qingbo Xu,Shu Ye +16 more
TL;DR: In this article, the authors investigated whether chromosome 10q11.21 influences common carotid intima-media thickness (IMT) and atherosclerosis and whether it is associated with stromal cell-derived factor-1α (SDF-α) plasma levels.
Journal ArticleDOI
The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure
Bernadet T. Santema,Michelle Chan,Jasper Tromp,Martin M Dokter,Haye H. van der Wal,Johanna E. Emmens,Janny Takens,Nilesh J. Samani,Nilesh J. Samani,Leong L. Ng,Leong L. Ng,Chim C. Lang,Peter van der Meer,Jozine M. ter Maaten,Kevin Damman,Kenneth Dickstein,Kenneth Dickstein,John G.F. Cleland,John G.F. Cleland,Faiez Zannad,Stefan D. Anker,Marco Metra,Pim van der Harst,Rudolf A. de Boer,Dirk J. van Veldhuisen,Michiel Rienstra,Carolyn S.P. Lam,Adriaan A. Voors +27 more
TL;DR: In patients with HF, NT-proBNP is significantly influenced by underlying AF at time of measurement and not by previous episodes of AF, whereas the levels of GDF-15 are not influenced by the presence of AF.