Nils Adey

TL;DR: A draft sequence of the rice genome for the most widely cultivated subspecies in China, Oryza sativa L. ssp.indica, by whole-genome shotgun sequencing is produced, with a large proportion of rice genes with no recognizable homologs due to a gradient in the GC content of rice coding sequences.

TL;DR: Using logistic regression analysis, this work provides a method for evaluating the probability of a woman's carrying a deleterious BRCA1 mutation for a wide range of cases, which can be an important tool for clinicians as they incorporate genetic susceptibility testing into their medical practice.

TL;DR: Threonine phosphorylation of the MMAC1/ PTEN-PDZBD peptide inhibited both microtiter plate binding to the hDLG and hMAST205 PDZ domains and coprecipitation of the Mr 140,000 and > 200,000 proteins, but promoted coprecIPitation of proteins of approximately Mr 90, thousands and Mr 120,000 from A431 cell lysate.

TL;DR: It is demonstrated that activation of the actin-binding activity of vinculin requires steps other than or in addition to the binding of PI4,5P2, and that phosphatidylinositol 4,5-bisphosphate inhibits the interaction of purified tail domain with F-actin.

TL;DR: This study has demonstrated that conformationally constrained peptides isolated from a phage library acted as specific, Ca2+-dependent CaM ligands.