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Niranjala J.K. Tillakaratne
Researcher at University of California, Los Angeles
Publications - 48
Citations - 6157
Niranjala J.K. Tillakaratne is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Spinal cord & Glutamate decarboxylase. The author has an hindex of 30, co-authored 47 publications receiving 5906 citations. Previous affiliations of Niranjala J.K. Tillakaratne include University of California & University of California, Irvine.
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Journal ArticleDOI
Two genes encode distinct glutamate decarboxylases.
TL;DR: The brain contains two forms of the GABA synthetic enzyme glutamate decarboxylase (GAD), which differ in molecular size, amino acid sequence, antigenicity, cellular and subcellular location, and interaction with the GAD cofactor pyridoxal phosphate.
Journal ArticleDOI
Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms
Monique Esclapez,Niranjala J.K. Tillakaratne,Daniel L. Kaufman,Allan J. Tobin,Carolyn R. Houser +4 more
TL;DR: The findings suggest that the two isoforms of GAD are present in most classes of GABA neurons but that they are not similarly distributed within the neurons.
Journal ArticleDOI
Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene
Ding-Fang Bu,Mark G. Erlander,B. C. Hitz,Niranjala J.K. Tillakaratne,Daniel L. Kaufman,C. B. Wagner-Mcpherson,G. A. Evans,Allan J. Tobin +7 more
TL;DR: The isolation and sequencing of cDNAs encoding two human glutamate decarboxylases each derive from a single separate gene should allow the bacterial production of test antigens for the diagnosis and prediction of insulin-dependent diabetes mellitus.
Journal ArticleDOI
Plasticity of the spinal neural circuitry after injury
TL;DR: Rehabilitative efforts combining locomotor training pharmacological means and/or spinal cord electrical stimulation paradigms will most likely result in more effective methods of recovery than using only one intervention.
Journal ArticleDOI
Retraining the injured spinal cord
V. Reggie Edgerton,Ray D. de Leon,Susan J. Harkema,John A. Hodgson,Nikolas London,David J. Reinkensmeyer,Roland R. Roy,Robert J. Talmadge,Niranjala J.K. Tillakaratne,Wojciech K. Timoszyk,Allan J. Tobin +10 more
TL;DR: Concepts and observations demonstrate that the spinal cord can interpret complex afferent information and generate the appropriate motor task; and motor ability can be defined to a large degree by training.