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Noboru Mizushima

Researcher at University of Tokyo

Publications -  305
Citations -  127807

Noboru Mizushima is an academic researcher from University of Tokyo. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 124, co-authored 273 publications receiving 111986 citations. Previous affiliations of Noboru Mizushima include National Institute for Basic Biology, Japan & Graduate University for Advanced Studies.

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Journal ArticleDOI

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Yukiko Kabeya, +13 more
- 01 Nov 2000 - 
TL;DR: It is demonstrated that the rat microtubule‐associated protein 1 light chain 3 (LC3), a homologue of Apg8p essential for autophagy in yeast, is associated to the autophagosome membranes after processing.
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Autophagy fights disease through cellular self-digestion

Noboru Mizushima, +3 more
- 28 Feb 2008 - 
TL;DR: Understanding autophagy may ultimately allow scientists and clinicians to harness this process for the purpose of improving human health, and to play a role in cell death.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Autophagy: Renovation of Cells and Tissues

Noboru Mizushima, +1 more
- 11 Nov 2011 - 
TL;DR: It is explored how recent mouse models in combination with advances in human genetics are providing key insights into how the impairment or activation of autophagy contributes to pathogenesis of diverse diseases, from neurodegenerative diseases such as Parkinson disease to inflammatory disorders such as Crohn disease.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.