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Author

Nobuaki Taniguchi

Other affiliations: Yale University, Baylor University
Bio: Nobuaki Taniguchi is an academic researcher from Tohoku University. The author has contributed to research in topics: Enantioselective synthesis & Michael reaction. The author has an hindex of 15, co-authored 64 publications receiving 539 citations. Previous affiliations of Nobuaki Taniguchi include Yale University & Baylor University.


Papers
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Journal ArticleDOI
TL;DR: Alkylation enantioselective des dianions derives des monoesters chiraux d'acides maloniques monosubstitues avec des halogenures d'alkyles as discussed by the authors.
Abstract: Alkylation enantioselective des dianions derives des monoesters chiraux d'acides maloniques monosubstitues avec des halogenures d'alkyles

53 citations

Journal ArticleDOI
TL;DR: In this paper, the treatment of α,β-unsaturated esters having a ketone function at an appropriate position with either TBDMSOTf in the presence of Et 3 N or TMSI (TMS) 2 NH provided, via a tandem intramolecular Michael-aldol reaction sequence, several different types of cyclobutane derivatives.
Abstract: The treatment of α,β-unsaturated esters having a ketone function at an appropriate position with either TBDMSOTf in the presence of Et 3 N or TMSI in the presence of (TMS) 2 NH provided, via a tandem intramolecular Michael-aldol reaction sequence, several different types of cyclobutane derivatives. The two reaction conditions were complementary. Tricyclo[4.2.1.03-8]nonanes 34 and 35, tricyclo[5.1.1.0 3,8 ]nonane 40, tricyclo[5.4.0.0 3,7 ]undecane 51, tetracyclo[5.4.0.0 3,7 .0 9,11 ]undecane 45, and the bicyclo[3.2.0]heptanes 36, 57, and 38, which have structures either partially or completely similar to those of endiandric acids A (1a), B (1b), and C (2), trihydroxydecipiadiene (3), lintenone (4), italicene (3), and filifolone (6), were stereoselectively synthesized by the tandem reaction

46 citations

Journal ArticleDOI
TL;DR: The radical cyclization of (±)-(E)-3-((2-(bromomethyl)butoxy)carbonyl)-prop-2-enoates (11) and (12) were carried out with (TMS) 3 SiH or Bu 3 SnH in the presence of AIBN.
Abstract: The radical cyclizations of (±)-(E)-3-((2-(bromomethyl)butoxy)carbonyl)- prop-2-enoates (11) and (12) and (±)-ethyl (E)-3-{N-[2-(bromomethyl)- butyl]-N-[2-(3-indolyl)ethyl]carbamoyl}prop-2-enoate (25) were carried out with (TMS) 3 SiH or Bu 3 SnH in the presence of AIBN. (-)-(2S)-2- ((tert-Butyldimethylsilyloxy)methyl)butan-1-ol (6), which was prepared by two different methods, was converted into (+)-25. The radical cycli- zation of(+)-25 produced piperidinone (18) as a diastereomeric mixture, which was transformed into tacamonine (1)

36 citations

Journal ArticleDOI
TL;DR: Both enantiomers of the menthyl halfesters (10) and (23) of ethylmalonic acid were converted into (+)-(4S,5R)-4-(2-benzyloxyethyl)-5-ethyl-3,4,5,6-tetrahydro-2-pyrone (18) as discussed by the authors.
Abstract: Both enantiomers of the menthyl half-esters (10) and (23) of ethylmalonic acid were converted into(+)-(4S,5R)-4-(2-benzyloxyethyl)-5-ethyl-3,4,5,6-tetrahydro-2-pyrone (18). A mixture of the trans-(18) and cis-lactones (19) in a ratio of ca. 4 : 1 was prepared by way of radical cyclisation of the (E)-α,β-unsaturated esters (16), while the former (18) was synthesised with high stereoselection by the cyclisation of the (Z)-esters (26). The lactone (18) was enantioselectively transformed into (–)-protoemetimol (5) and (–)-protoemetine (4), correlated to (–)-emetine (1) and (–)-tubulosine (3).

32 citations


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Book
11 Sep 2006
TL;DR: It is shown that domino reactions initiated by oxidation or reduction or reduction, as well as other mechanisms, can be inhibited by various materials, such as Na6(CO3)(SO4), Na2SO4, Na2CO3, and so on.
Abstract: Introduction Cationic domino reactions Anionic domino reactions Radical domino reactions Pericyclic domino reactions Photochemically induced domino processes Transition metal catalysis Domino reactions initiated by oxidation or reduction Enzymes in domino reactions Multicomponent reactions Special techniques in domino reactions

1,337 citations