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Nobuaki Taniguchi

Researcher at Tohoku University

Publications -  64
Citations -  558

Nobuaki Taniguchi is an academic researcher from Tohoku University. The author has contributed to research in topics: Enantioselective synthesis & Intramolecular force. The author has an hindex of 15, co-authored 64 publications receiving 539 citations. Previous affiliations of Nobuaki Taniguchi include Yale University & Baylor University.

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Total Synthesis of (±)-Phomoidride D

TL;DR: This highly efficient and stereoselective approach provides rapid assembly of the carbocyclic core by way of a tandem phenolic oxidation/intramolecular Diels-Alder cycloaddition.
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Enantioselective construction of quaternary stereogenic centres possessing a fluorine atom

TL;DR: Fluorination of methyl (1R,3R,4S)-8-phenylmenthyl methylmalonates using lithium hexamethyl-disilazide and 1-fluoro-2,4,6-trimethylpyridinium triflate (trifluoromethanesulfonate) gave the (R)-3 and (S)-4 isomers in a 3.8 : 1 ratio, while fluorination of ethyl-, propyl- and benzyl-malonsates 10, 11 and 12 provided
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Asymmetric syntheses of chiral propane-1,3-diols starting from malonic acid

TL;DR: In this paper, the synthesis of chiral intermediates having one tertiary asymmetric center was carried out via chiral half-esters of monoalkylmalonic acids, and enantioselective preparation of unsymmetrical propane-1,3-diol derivatives was achieved by the use of 8-phenylmenthyl half-ester.
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A Total Synthesis of (±)-Tacamonine (Pseudovincamone I) through Radical Cyclization

TL;DR: The radical cyclization of the bromo ester (11), prepared from 2-hydroxymethylbutan-1-ol (7), giving the diastereoisomeric mixture of lactones (12) was examined under various conditions.
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A stereoselective total synthesis of (±)-dihydrocorynantheol via radical cyclisation

TL;DR: Stereoselective total synthesis of (±)-dihydrocorynantheol has been accomplished via radical cyclisation of a bromoacetal of a homoallylic alcohol.