N
Nobuyoshi Yasuda
Researcher at Merck & Co.
Publications - 164
Citations - 2647
Nobuyoshi Yasuda is an academic researcher from Merck & Co.. The author has contributed to research in topics: Catalysis & Enantioselective synthesis. The author has an hindex of 28, co-authored 163 publications receiving 2439 citations. Previous affiliations of Nobuyoshi Yasuda include Stanford University.
Papers
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Journal ArticleDOI
Lithium Alkoxides of Cinchona Alkaloids as Chiral Controllers for Enantioselective Acetylide Addition to Cyclic N-Acyl Ketimines
Journal ArticleDOI
A new general method for preparation of N-methoxy-N-methylamides. Application in direct conversion of an ester to a ketone
J. Michael Williams,Ronald B. Jobson,Nobuyoshi Yasuda,G. Marchesini,Ulf-H. Dolling,Edward J. J. Grabowski +5 more
TL;DR: In this article, the azasteroid 5α-reductase inhibitor MK-0434 is described for the direct conversion of a highly hindered ester to a ketone, and the reaction of an ester with N, O -dimethylhydroxylamine and a suitable organomagnesium reagent or lithium amide base is described.
Book ChapterDOI
Palladium-Catalyzed Cross-Coupling Reactions in the Synthesis of Pharmaceuticals
Anthony O. King,Nobuyoshi Yasuda +1 more
Journal ArticleDOI
Contemporary Asymmetric Phase Transfer Catalysis: Large-Scale Industrial Applications
Jiajing Tan,Nobuyoshi Yasuda +1 more
TL;DR: Asymmetric phase transfer catalysis has been recognized as an approach that is greener and more sustainable than synthetic alternatives and has evolved into one of the most practical methods in challenging enantioselective synthesis.