Noel Tulipan

TL;DR: Prenatal surgery for myelomeningocele reduced the need for shunting and improved motor outcomes at 30 months but was associated with maternal and fetal risks and increased risk of preterm delivery and uterine dehiscence at delivery.

TL;DR: Larger ventricles at initial screening are associated with an increased need for shunting among those undergoing fetal surgery for myelomeningocele and care should be exercised in recommending prenatal surgery when the ventricle size is 15 mm or larger because prenatal surgery does not appear to improve outcome in this group.

TL;DR: This research presents a novel and scalable approach called “informed consent” that allows for real-time decision-making about whether or not to admit a child to hospital for treatment with a serious medical condition.

TL;DR: It is concluded that older patients with preexisting cognitive impairment should not be included in future studies until the benefits are more clearly established and the distinct and persistent improvement seen in some of the younger patients warrants the initiation of a well-designed, randomized, and controlled trial of adrenal medullary autotransplantation.

TL;DR: With current technology, in utero repair of congenital myelomeningocele through a hysterotomy appears to be technically superior to procedures performed endoscopically.