The dark side of miracle plant-Aloe vera: a review

Aloe vera and its two bioactive constituents in alleviation of diabetes -proteomic & mechanistic insights.

The aim of the study is to evaluate the composition of lyophilisates obtained from Aloe arborescens leaf gel at the age of one to four years The leaves were obtained from controlled crops, which allowed to exclude environmental factors as variables It was confirmed that the lyophilisates obtained from different years of Aloe arborescens leaf gel varied in chromatographic analyses in terms of aloin A and aloenin A content (high-performance liquid chromatography with diode-array detection HPLC-DAD, high-performance liquid chromatography with tandem mass spectrometric detection HPLC-MS/MS) Similarly, while testing the phenolic acids and the sum of polyphenols content, differences in their levels in leaf gel lyophilisates from plants of individual years were observed (spectrophotometric method UV-VIS) The lyophilisate composition analysis showed that the one-year-old leaves were characterized by the highest content of aloin A and aloenin A While the content of polyphenols, including phenolic acids, was higher in the leaves of older plants The antioxidant potential of the tested lyophilisates was assessed simultaneously Regardless of the research model used (CUPRAC, DPPH, ABTS), an antioxidant effect was noted for Aloe arborescens leaves

Analysis of the Composition of Lyophilisates Obtained from Aloe arborescens Gel of Leaves of Different Ages from Controlled Crops.

Current status of Aloe-based nanoparticle fabrication, characterization and their application in some cutting-edge areas

Design and development of novel formulation of Aloe Vera nanoemulsion gel contained erythromycin for topical antibacterial therapy: In vitro and in vivo assessment

The therapeutic and pharmacological properties of plant bioactive constituents still continue to be the subject of many researches. Species of the Aloe genus have a history in folklore medicine and they have gained more attention over the years due to their various medicinal properties. Phytochemical studies have revealed that the Aloe species contain a number of constituents, such as polyphenols, phytosterols, polysaccharides, proteins, amino acids, chromones, and mineral elements. A comprehensive evidence-based review on the different constituents of Aloe species is needed in order to understand the benefits imparted by them. This review presents an overview of the bioactive components of the Aloe genus with emphasis on their anti-diabetic potential and other pharmacological benefits. This information will be beneficial for the advancement of new strategies of Aloe formulations with therapeutic and economical value in the near future. Furthermore, the potential applications and constraints have also been discussed so as to provide a wider prospect for research in this field for the benefit of the society.

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Noor Ayesha

Papers

Bioactive constituents of the genus Aloe and their potential therapeutic and pharmacological applications: A review