Norbert Lameire

TL;DR: The 2006 KDIGO Controversies Conference on CKD was convened to consider six major topics: CKD classification, CKD screening and surveillance, public policy for CKD, CVD and CVD risk factors as risk factors for development and progression of CKd, association of CKD with chronic infections, and (6) association of CJD with cancer.

TL;DR: Correcting the principal mediators of hyperglycaemia‐induced endothelial dysfunction may be activation of protein kinase C, increased activity of the polyol pathway, non‐enzymatic glycation and oxidative stress, as well as administration of ACE inhibitors and folate has been shown to improve endothelium‐dependent vasodilation in diabetes.

TL;DR: VEGF is identified as a pathogenetic link between hyperglycemia and early renal dysfunction in diabetes and may prove useful as a therapeutic strategy for the treatment of early diabetic nephropathy.

TL;DR: The most practical approach to risk prediction is based on a simple model incorporating renal function and diabetes mellitus, using data from large databases of percutaneous coronary intervention patients.