Norbert Opitz

TL;DR: An optical fluorescence based intravascular blood gas monitoring system has been developed which is particularly suited for the critical care and surgical settings and which has a sensor probe that can be introduced into the patient via a radial artery catheter.

TL;DR: This work investigated the partitioning of semisynthetic fully functional lipidated K-Ras4B proteins into heterogeneous anionic model membranes and membranes composed of viral lipid extracts and forms new protein-containing fluid domains that are recruiting multivalent acidic lipids by an effective, electrostatic lipid sorting mechanism.

TL;DR: The present study focuses on the principles of aggregation and amyloid formation of hIAPP in the presence of model raft membranes and reveals elevated cytotoxicity of hiAPP oligomers on INS‐1E cells.

TL;DR: In this paper, the authors performed biochemical studies to analyze the implications of myristoylation on the conformation of Nef in aqueous solution, and they showed that Nef is only a weak lipidation anchor for membrane attachment.

TL;DR: Interaction studies with the pancreatic β‐cell line INS‐1E revealed that growing IAPP fibrils also incorporate substantial amounts of cellular membranes in vivo, alluding to its potential use in developing therapeutic strategies against T2DM.