N
Norbert Stefan
Researcher at University of Tübingen
Publications - 367
Citations - 26598
Norbert Stefan is an academic researcher from University of Tübingen. The author has contributed to research in topics: Insulin resistance & Type 2 diabetes. The author has an hindex of 80, co-authored 338 publications receiving 22637 citations. Previous affiliations of Norbert Stefan include University Hospital Heidelberg & National Institutes of Health.
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Journal ArticleDOI
Identification and characterization of metabolically benign obesity in humans.
Norbert Stefan,Konstantinos Kantartzis,Jürgen Machann,Fritz Schick,Claus Thamer,Kilian Rittig,Bernd Balletshofer,Fausto Machicao,Andreas Fritsche,Hans-Ulrich Häring +9 more
TL;DR: A metabolically benign obesity that is not accompanied by insulin resistance and early atherosclerosis exists in humans and ectopic fat in the liver may be more important than visceralfat in the determination of such a beneficial phenotype in obesity.
Journal ArticleDOI
Identification of Serum Metabolites Associated With Risk of Type 2 Diabetes Using a Targeted Metabolomic Approach
Anna Floegel,Norbert Stefan,Zhonghao Yu,Kristin Mühlenbruch,Dagmar Drogan,Hans-Georg Joost,Andreas Fritsche,Hans-Ulrich Häring,Martin Hrabě de Angelis,Annette Peters,Michael Roden,Cornelia Prehn,Rui Wang-Sattler,Thomas Illig,Matthias B. Schulze,Jerzy Adamski,Heiner Boeing,Tobias Pischon +17 more
TL;DR: The data indicate that metabolic alterations, including sugar metabolites, amino acids, and choline-containing phospholipids, are associated early on with a higher risk of T2D.
Journal ArticleDOI
High Alanine Aminotransferase Is Associated With Decreased Hepatic Insulin Sensitivity and Predicts the Development of Type 2 Diabetes
Barbora Vozarova,Norbert Stefan,Robert S. Lindsay,Aramesh Saremi,Richard E. Pratley,Clifton Bogardus,P. Antonio Tataranni +6 more
TL;DR: It is indicated that high ALT is a marker of risk for type 2 diabetes and a potential role of the liver in the pathogenesis of type 2abetes is suggested.
Journal ArticleDOI
Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance.
Nina F. Schwenzer,Fabian Springer,Christina Schraml,Norbert Stefan,Jürgen Machann,Fritz Schick +5 more
TL;DR: In the present review, available imaging modalities (ultrasound, computed tomography, magnetic resonance imaging and proton magnetic resonance spectroscopy) are presented which are employed to detect or even quantify the fat content of the liver.
Journal ArticleDOI
Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications
TL;DR: The observational studies that gave rise to the idea of metabolically healthy obesity are described and the key parameters that can help to distinguish it from the general form of obesity are discussed.