Nosheen Nazar

Bio: Nosheen Nazar is an academic researcher from Bahauddin Zakariya University. The author has contributed to research in topics: Materials science & Dielectric. The author has an hindex of 6, co-authored 12 publications receiving 391 citations. Previous affiliations of Nosheen Nazar include The Islamia University of Bahawalpur Pakistan & Islamia University.

Green synthesis of iron oxide nanoparticles using pomegranate seeds extract and photocatalytic activity evaluation for the degradation of textile dye

Abstract: Iron oxide nanoparticles (Fe2O3 NPs) were fabricated through green route using pomegranate (Punica granatum) seeds extract. The Fe2O3 NPs were characterized by UV–vis, XRD, EDX, SEM and AFM techniques. The adopted green rout furnished semi spherical Fe2O3 NPs, uniformly distributed and particle size in the range of 25–55 nm. The LCMS/MS was performed for the identification of biomolecule present in the extract of pomegranate seeds and p-hydroxy benzoic acid, gallic acid, methyl gallate, catechin, kaempferol-3-O-sophoroside, 3-deoxyflavonoids, magnolol, ferulic acid, vanillic acid and pinocembrin along with other minor constituents were detected in the extracts using for Fe2O3 NPs. The synthesized Fe2O3 NPs showed excellent photocatalytic activity against reactive blue under UV light irradiation and maximum degradation of 95.08% was achieved with 56 min of reaction time. In view of promising activity, the Fe2O3 NPs could be used photocatalyst for the degradation of dyes in wastewater and pomegranate seeds extract can be applied as eco-benign and cost effective approach for Fe2O3 NPs synthesis.

Secondary Metabolites in the Green Synthesis of Metallic Nanoparticles

Abstract: The ability of organisms and organic compounds to reduce metal ions and stabilize them into nanoparticles (NPs) forms the basis of green synthesis. To date, synthesis of NPs from various metal ions using a diverse array of plant extracts has been reported. However, a clear understanding of the mechanism of green synthesis of NPs is lacking. Although most studies have neglected to analyze the green-synthesized NPs (GNPs) for the presence of compounds derived from the extract, several studies have demonstrated the conjugation of sugars, secondary metabolites, and proteins in these biogenic NPs. Despite several reports on the bioactivities (antimicrobial, antioxidant, cytotoxic, catalytic, etc.) of GNPs, only a handful of studies have compared these activities with their chemically synthesized counterparts. These comparisons have demonstrated that GNPs possess better bioactivities than NPs synthesized by other methods, which might be attributed to the presence of plant-derived compounds in these NPs. The ability of NPs to bind with organic compounds to form a stable complex has huge potential in the harvesting of precious molecules and for drug discovery, if harnessed meticulously. A thorough understanding of the mechanisms of green synthesis and high-throughput screening of stabilizing/capping agents on the physico-chemical properties of GNPs is warranted to realize the full potential of green nanotechnology.

Biogenesis of metal nanoparticles and their pharmacological applications: present status and application prospects

Abstract: Green chemistry approaches for the synthesis of metallic nanoparticles have become a new and promising field of research in recent years. Synthesis of metal nanoparticles [like gold (Au), silver (Ag), lead (Pb), platinum (Pt), copper (Cu), iron (Fe), cadmium (Cd), and other metal oxides such as titanium oxide (TiO), zinc oxide (ZnO), etc.] by various chemical and physical approaches as well as the biological approaches mediated by number of microorganisms have been actively found. Plant-mediated synthesis approaches are found to be more reliable and economic route to synthesize these metal nanoparticles. Owing to the biodiversity of plant biomasses, the actual mechanism by which the plant constituents have contributed to the synthetic process is yet to be fully known. Although the feasibility of controlling, the size and shape of nanoparticles by variation in reaction conditions have been demonstrated in many studies. Conventionally, nanoparticles are synthesized by chemicals and physicochemical methods using several chemicals which later on become accountable for various risk due to their general toxicity, so that solving the objective biological approaches is coming up to fill these gaps. The plant-mediated synthesis process undergoes highly controlled approaches for making them suitable for metal nanoparticle synthesis. In addition, biological synthesis of metallic nanoparticles is inexpensive, one-step, and eco-friendly method. In addition, the plant-mediated nanoparticles are used as potential pharmaceutical agents for various diseases such as malaria, HIV, cancer, hepatitis, and other diseases. Including this some other relevant information regarding nanopharmaceutical products, companies that are involve in the manufacturing and commercialization process and their clinical trial status are also discussed. This review article gives an overview of the plant-mediated synthesis of metal nanoparticles, possible compounds, and mechanisms that might be responsible for the reduction process as well as the potential pharmacological applications, currently available nanopharmaceutical products and their marketing status.

Green synthesis of iron oxide nanoparticles using pomegranate seeds extract and photocatalytic activity evaluation for the degradation of textile dye

Abstract: Iron oxide nanoparticles (Fe2O3 NPs) were fabricated through green route using pomegranate (Punica granatum) seeds extract. The Fe2O3 NPs were characterized by UV–vis, XRD, EDX, SEM and AFM techniques. The adopted green rout furnished semi spherical Fe2O3 NPs, uniformly distributed and particle size in the range of 25–55 nm. The LCMS/MS was performed for the identification of biomolecule present in the extract of pomegranate seeds and p-hydroxy benzoic acid, gallic acid, methyl gallate, catechin, kaempferol-3-O-sophoroside, 3-deoxyflavonoids, magnolol, ferulic acid, vanillic acid and pinocembrin along with other minor constituents were detected in the extracts using for Fe2O3 NPs. The synthesized Fe2O3 NPs showed excellent photocatalytic activity against reactive blue under UV light irradiation and maximum degradation of 95.08% was achieved with 56 min of reaction time. In view of promising activity, the Fe2O3 NPs could be used photocatalyst for the degradation of dyes in wastewater and pomegranate seeds extract can be applied as eco-benign and cost effective approach for Fe2O3 NPs synthesis.