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Nuno Milhazes
Researcher at University of Porto
Publications - 43
Citations - 3850
Nuno Milhazes is an academic researcher from University of Porto. The author has contributed to research in topics: Meth- & Methamphetamine. The author has an hindex of 29, co-authored 43 publications receiving 3427 citations. Previous affiliations of Nuno Milhazes include Health Sciences North & University of Coimbra.
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Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.
TL;DR: The present work is to survey the information published or abstracted from 1990 till 2003, which is mainly related to the occurrence, synthesis and biological importance of simple coumarins and some analogues, such as biscou marins and triscoumarins.
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Phenolic acid derivatives with potential anticancer properties--a structure-activity relationship study. Part 1: methyl, propyl and octyl esters of caffeic and gallic acids.
Sónia M. Fiuza,Catarina Gomes,L.J. Teixeira,M.T. Girão da Cruz,Maria Natalia Dias Soeiro Cordeiro,Nuno Milhazes,Nuno Milhazes,Fernanda Borges,Fernanda Borges,Maria Paula M. Marques +9 more
TL;DR: Marked structure-activity relationships (SARs)--namely the number of hydroxyl ring substituents--were found to rule the biological effect of such systems.
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Anticancer activity of phenolic acids of natural or synthetic origin: a structure-activity study.
Catarina Gomes,Teresa Girao Da Cruz,José L. Andrade,Nuno Milhazes,Fernanda Borges,M. Paula M. Marques +5 more
TL;DR: Several phenolic acids-caffeic and gallic acid derivatives-were synthesized and screened for their potential antiproliferative and cytotoxic properties, in different human cancer cell lines: mammary gland and cervix adenocarcinomas and lymphoblastic leukemia, and verified, for the types of cancer investigated, that the trihydroxylated derivatives yielded better results.
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Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances
TL;DR: This perspective provides the reader with an update of an earlier article entitled "Chromone: A Valid Scaffold in Medicinal Chemistry" and is mainly focused on chromones of biological interest, including those isolated from natural sources.
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Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity.
TL;DR: The scope of this review encompasses the importance of furocoumarins and the most important developments in this field that have been made in recent years, with particular emphasis placed on the aspects related to medicinal chemistry.