Author
Nuntavan Bunyapraphatsara
Bio: Nuntavan Bunyapraphatsara is an academic researcher from Mahidol University. The author has contributed to research in topics: Essential oil & Histamine. The author has an hindex of 21, co-authored 50 publications receiving 1832 citations.
Papers published on a yearly basis
Papers
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TL;DR: The lines of evidence suggest that the aqueous extracts from the dried calyx of roselle possess both antioxidant effects against LDL oxidation and hypolipidemic effects in vivo, however, its mechanism(s) of action remains to be elucidated.
249 citations
TL;DR: The results suggest the potential of aloe vera juice for use as an antidiabetic agent in patients with diabetes.
198 citations
TL;DR: Aloe vera juice significantly reduced levels of fasting blood glucose within two weeks and of triglycerides within four weeks and showed no effect on cholesterol levels and had no toxic effects on kidney or liver function as assessed by blood chemistry.
191 citations
TL;DR: Data suggest therapeutic potential of these plant extracts, investigated for their intracellular activities against herpes simplex viruses, which contained both anti-HSV-1 and -2 activities, as determined by plaque inhibition assay.
164 citations
TL;DR: Thirteen Thai medicinal plants were investigated for their activity against MRSA, and Garcinia mangostana was identified as the most potent plant, and its activity was traced to the prenylated xanthone, alpha-mangostin.
114 citations
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TL;DR: This review covers the literature published in 2014 for marine natural products, with 1116 citations referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms.
4,649 citations
TL;DR: The aim of this review is to further highlight recently discovered effects and applications of the leaf gel of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation.
Abstract: Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological activities include promotion of wound healing, antifungal activity, hypoglycemic or antidiabetic effects antiinflammatory, anticancer, immunomodulatory and gastroprotective properties. While the known biological activities of A. vera will be briefly discussed, it is the aim of this review to further highlight recently discovered effects and applications of the leaf gel. These effects include the potential of whole leaf or inner fillet gel liquid preparations of A. vera to enhance the intestinal absorption and bioavailability of co-administered compounds as well as enhancement of skin permeation. In addition, important pharmaceutical applications such as the use of the dried A. vera gel powder as an excipient in sustained release pharmaceutical dosage forms will be outlined.
889 citations
TL;DR: There is still insufficient evidence to draw definitive conclusions about the efficacy of individual herbs and supplements for diabetes; however, they appear to be generally safe.
Abstract: OBJECTIVE —To conduct a systematic review of the published literature on the efficacy and safety of herbal therapies and vitamin/mineral supplements for glucose control in patients with diabetes. RESEARCH DESIGN AND METHODS —We conducted an electronic literature search of MEDLINE, OLDMEDLINE, Cochrane Library Database, and HealthSTAR, from database inception to May 2002, in addition to performing hand searches and consulting with experts in the field. Available clinical studies published in the English language that used human participants and examined glycemic control were included. Data were extracted in a standardized manner, and two independent investigators assessed methodological quality of randomized controlled trials using the Jadad scale. RESULTS —A total of 108 trials examining 36 herbs (single or in combination) and 9 vitamin/mineral supplements, involving 4,565 patients with diabetes or impaired glucose tolerance, met the inclusion criteria and were analyzed. There were 58 controlled clinical trials involving individuals with diabetes or impaired glucose tolerance (42 randomized and 16 nonrandomized trials). Most studies involved patients with type 2 diabetes. Heterogeneity and the small number of studies per supplement precluded formal meta-analyses. Of these 58 trials, the direction of the evidence for improved glucose control was positive in 76% (44 of 58). Very few adverse effects were reported. CONCLUSIONS —There is still insufficient evidence to draw definitive conclusions about the efficacy of individual herbs and supplements for diabetes; however, they appear to be generally safe. The available data suggest that several supplements may warrant further study. The best evidence for efficacy from adequately designed randomized controlled trials (RCTs) is available for Coccinia indica and American ginseng. Chromium has been the most widely studied supplement. Other supplements with positive preliminary results include Gymnema sylvestre , Aloe vera , vanadium, Momordica charantia , and nopal.
853 citations
TL;DR: Research since the 1986 review has largely upheld the therapeutic claims made in the earlier papers and indeed extended them into other areas and a common theme running though much recent research is the immunomodulatory properties of the gel polysaccharides, especially the acetylated mannans from Aloe vera, which are now a proprietary substance covered by many patents.
815 citations
TL;DR: In vitro and in vivo studies as well as some clinical trials provide some evidence mostly for phytochemically poorly characterised Hs extracts which showed antibacterial, anti-oxidant, nephro- and hepato-protective, renal/diuretic effect, effects on lipid metabolism (anti-cholesterol), anti-diabetic and anti-hypertensive effects among others.
615 citations