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Nuria Tubío-Santamaría
Researcher at Greifswald University Hospital
Publications - 2
Citations - 16
Nuria Tubío-Santamaría is an academic researcher from Greifswald University Hospital. The author has contributed to research in topics: Medicine. The author has an hindex of 1, co-authored 1 publications receiving 3 citations.
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Immunoproteasome Function in Normal and Malignant Hematopoiesis.
TL;DR: In this article, the authors reviewed data on immunoproteasome function and inhibition in hematopoietic cells and hematologic cancers and showed promising preliminary results in pre-clinical studies and one inhibitor is currently being investigated in clinical trials for the treatment of multiple myeloma.
Journal ArticleDOI
Histone demethylase KDM4C is a functional dependency in JAK2-mutated neoplasms
Philipp Ernst,Tina M. Schnöder,Nicolas Huber,Florian Perner,Ashok Kumar Jayavelu,Theresa Eifert,Chen Jen Hsu,Nuria Tubío-Santamaría,Carl Crodel,Martin Ungelenk,Christian A. Hübner,Joachim H. Clement,Andreas Hochhaus,Florian H. Heidel +13 more
TL;DR: KDM4C is established as a specific dependency and therapeutic target in JAK2-mutated cells that is essential for oncogenic signaling and prevents induction of senescence.