O
Olaf Wolkenhauer
Researcher at University of Rostock
Publications - 354
Citations - 8624
Olaf Wolkenhauer is an academic researcher from University of Rostock. The author has contributed to research in topics: Systems biology & Gene. The author has an hindex of 45, co-authored 329 publications receiving 7422 citations. Previous affiliations of Olaf Wolkenhauer include Chhattisgarh Swami Vivekanand Technical University & Case Western Reserve University.
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Journal ArticleDOI
Do simple models lead to generality in ecology
Matthew R. Evans,Volker Grimm,Karin Johst,Tarja Knuuttila,Rogier De Langhe,C. M. Lessells,Martina Merz,Maureen A. O’Malley,Steve H. Orzack,Michael Weisberg,Darren J. Wilkinson,Olaf Wolkenhauer,Tim G. Benton +12 more
TL;DR: It is argued here that viewing simple models as the main way to achieve generality may be an obstacle to the progress of ecological research, and how complex models can be both desirable and general.
Journal ArticleDOI
Systems medicine and integrated care to combat chronic noncommunicable diseases
Jean Bousquet,Josep M. Antó,Peter J. Sterk,Ian M. Adcock,Kian Fan Chung,Josep Roca,Alvar Agusti,Christopher E. Brightling,Anne Cambon-Thomsen,Alfredo Cesario,Sonia Abdelhak,Stylianos E. Antonarakis,Antoine Avignon,Andrea Ballabio,Eugenio Baraldi,Alexander Baranov,Thomas Bieber,Joël Bockaert,Samir K. Brahmachari,Christian Brambilla,Jacques Bringer,Michel Dauzat,Ingemar Ernberg,Leonardo M. Fabbri,Philippe Froguel,David J. Galas,Takashi Gojobori,Peter Hunter,Christian Jorgensen,Francine Kauffmann,Philippe Kourilsky,Marek L. Kowalski,Doron Lancet,Claude Le Pen,Jacques Mallet,Bongani M. Mayosi,Jacques Mercier,Andres Metspalu,Joseph H. Nadeau,Grégory Ninot,Denis Noble,Mehmet Ozturk,Susanna Palkonen,Christian Préfaut,Klaus F. Rabe,Eric Renard,Richard G. Roberts,B. Samolinski,Holger J. Schünemann,Hans-Uwe Simon,Marcelo B. Soares,Giulio Superti-Furga,Jesper Tegnér,Sergio Verjovski-Almeida,Peter Wellstead,Olaf Wolkenhauer,Emiel F.M. Wouters,Rudi Balling,Anthony J. Brookes,Dominique Charron,Christophe Pison,Christophe Pison,Zhu Chen,Leroy Hood,Charles Auffray +64 more
TL;DR: An innovative, integrated, cost-effective health system to combat major non-communicable diseases (NCDs), including cardiovascular, chronic respiratory, metabolic, rheumatologic and neurologic disorders and cancers, which together are the predominant health problem of the 21st century is proposed.
Journal ArticleDOI
Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κ B Signal Transduction Pathway:
TL;DR: A new strategy for experimental design based on parameter sensitivity analysis is introduced, which identifies key parameters/variables in a signal transduction pathway model and can thereby provide experimental biologists with guidance on which proteins to consider for measurement.
Journal ArticleDOI
Systems biology: The reincarnation of systems theory applied in biology?
TL;DR: The domain of systems theory, its application to biology and the lessons that can be learned from the work of Robert Rosen are reviewed.
Book ChapterDOI
Fuzzy Clustering of Short Time-Series and Unevenly Distributed Sampling Points
TL;DR: A fuzzy time-series (FSTS) clustering algorithm is developed by incorporating the STS distance into the standard fuzzy clustering scheme and is able to measure similarity of shapes which are formed by the relative change of amplitude and the corresponding temporal information.