Olav Gaute Hellesø

Bio: Olav Gaute Hellesø is an academic researcher from University of Tromsø. The author has contributed to research in topics: Waveguide (optics) & Optical tweezers. The author has an hindex of 15, co-authored 49 publications receiving 792 citations. Previous affiliations of Olav Gaute Hellesø include LEMO & University of Southampton.

Sorting of polystyrene microspheres using a Y-branched optical waveguide

Abstract: We demonstrate how a Y-branched optical waveguide can be used for microparticle sorting. Polystyrene microparticles, optically guided in the waveguide’s evanescent field, are directed down the desired, more strongly illuminated, output branch. The output of a fibre laser at a wavelength of 1066 nm is coupled to the waveguide by direct butting. The power distribution between the two output branches is selected by the relative position of the fibre to the waveguide input facet. This provides a simple method for reliable particle sorting with very high probability of success under appropriate conditions. The method can be easily combined with other particle manipulation techniques of interest for micro total analysis systems of the future.

Structured illumination microscopy using a photonic chip

Abstract: Structured illumination microscopy (SIM) enables live-cell super-resolution imaging of subcellular structures at high speeds. At present, linear SIM uses free-space optics to illuminate the sample with the desired light patterns; however, such arrangements are prone to misalignment and add cost and complexity to the microscope. Here, we present an alternative photonic chip-based two-dimensional SIM approach (cSIM) in which the conventional glass sample slide in a microscope is replaced by a planar photonic chip that importantly both holds and illuminates the specimen. The photonic chip reduces the footprint of the light illumination path of SIM to around 4 × 4 cm2. An array of optical waveguides on the chip creates standing wave interference patterns at different angles, which illuminate the sample via evanescent fields. High-refractive-index silicon nitride waveguides allow a 2.3 times enhancement in imaging spatial resolution, exceeding the usual 2 times limit of SIM. In summary, cSIM offers a simple, stable and affordable approach for performing two-dimensional super-resolution imaging over a large field of view. The use of a photonic integrated circuit to both hold a biological sample and generate the necessary light patterns for structured illumination microscopy promises convenient super-resolution imaging.

Optical trapping and propulsion of red blood cells on waveguide surfaces

Abstract: We have studied optical trapping and propulsion of red blood cells in the evanescent field of optical waveguides. Cell propulsion is found to be highly dependent on the biological medium and serum proteins the cells are submerged in. Waveguides made of tantalum pentoxide are shown to be efficient for cell propulsion. An optical propulsion velocity of up to 6 µm/s on a waveguide with a width of ~6 µm is reported. Stable optical trapping and propulsion of cells during transverse flow is also reported.

Surface transport and stable trapping of particles and cells by an optical waveguide loop

Abstract: Waveguide trapping has emerged as a useful technique for parallel and planar transport of particles and biological cells and can be integrated with lab-on-a-chip applications. However, particles trapped on waveguides are continuously propelled forward along the surface of the waveguide. This limits the practical usability of the waveguide trapping technique with other functions (e.g. analysis, imaging) that require particles to be stationary during diagnosis. In this paper, an optical waveguide loop with an intentional gap at the centre is proposed to hold propelled particles and cells. The waveguide acts as a conveyor belt to transport and deliver the particles/cells towards the gap. At the gap, the diverging light fields hold the particles at a fixed position. The proposed waveguide design is numerically studied and experimentally implemented. The optical forces on the particle at the gap are calculated using the finite element method. Experimentally, the method is used to transport and trap micro-particles and red blood cells at the gap with varying separations. The waveguides are only 180 nm thick and thus could be integrated with other functions on the chip, e.g. microfluidics or optical detection, to make an on-chip system for single cell analysis and to study the interaction between cells.

Optical manipulation of nanoparticles and biomolecules in sub-wavelength slot waveguides.

Abstract: The ability to manipulate nanoscopic matter precisely is critical for the development of active nanosystems. Optical tweezers are excellent tools for transporting particles ranging in size from several micrometres to a few hundred nanometres. Manipulation of dielectric objects with much smaller diameters, however, requires stronger optical confinement and higher intensities than can be provided by these diffraction-limited systems. Here we present an approach to optofluidic transport that overcomes these limitations, using sub-wavelength liquid-core slot waveguides. The technique simultaneously makes use of near-field optical forces to confine matter inside the waveguide and scattering/adsorption forces to transport it. The ability of the slot waveguide to condense the accessible electromagnetic energy to scales as small as 60 nm allows us also to overcome the fundamental diffraction problem. We apply the approach here to the trapping and transport of 75-nm dielectric nanoparticles and lambda-DNA molecules. Because trapping occurs along a line, rather than at a point as with traditional point traps, the method provides the ability to handle extended biomolecules directly. We also carry out a detailed numerical analysis that relates the near-field optical forces to release kinetics. We believe that the architecture demonstrated here will help to bridge the gap between optical manipulation and nanofluidics.

1/f Noise Sources

Abstract: This survey deals with 1/f noise in homogeneous semiconductor samples. A distinction is made between mobility noise and number noise. It is shown that there always is mobility noise with an /spl alpha/ value with a magnitude in the order of 10/sup -4/. Damaging the crystal has a strong influence on /spl alpha/, /spl alpha/ may increase by orders of magnitude. Some theoretical models are briefly discussed none of them can explain all experimental results. The /spl alpha/ values of several semiconductors are given. These values can be used in calculations of 1/f noise in devices. >

Light at work: The use of optical forces for particle manipulation, sorting, and analysis

Abstract: We review the combinations of optical micro-manipulation with other techniques and their classical and emerging applications to non-contact optical separation and sorting of micro- and nanoparticle suspensions, compositional and structural analysis of specimens, and quantification of force interactions at the microscopic scale. The review aims at inspiring researchers, especially those working outside the optical micro-manipulation field, to find new and interesting applications of these methods.

Optical fiber nanowires and microwires: fabrication and applications

Abstract: Microwires and nanowires have been manufactured by using a wide range of bottom-up techniques such as chemical or physical vapor deposition and top-down processes such as fiber drawing. Among these techniques, the manufacture of wires from optical fibers provides the longest, most uniform and robust nanowires. Critically, the small surface roughness and the high-homogeneity associated with optical fiber nanowires (OFNs) provide low optical loss and allow the use of nanowires for a wide range of new applications for communications, sensing, lasers, biology, and chemistry. OFNs offer a number of outstanding optical and mechanical properties, including (1) large evanescent fields, (2) high-nonlinearity, (3) strong confinement, and (4) low-loss interconnection to other optical fibers and fiberized components. OFNs are fabricated by adiabatically stretching optical fibers and thus preserve the original optical fiber dimensions at their input and output, allowing ready splicing to standard fibers. A review of the manufacture of OFNs is presented, with a particular emphasis on their applications. Three different groups of applications have been envisaged: (1) devices based on the strong confinement or nonlinearity, (2) applications exploiting the large evanescent field, and (3) devices involving the taper transition regions. The first group includes supercontinuum generators, a range of nonlinear optical devices, and optical trapping. The second group comprises knot, loop, and coil resonators and their applications, sensing and particle propulsion by optical pressure. Finally, mode filtering and mode conversion represent applications based on the taper transition regions. Among these groups of applications, devices exploiting the OFN-based resonators are possibly the most interesting; because of the large evanescent field, when OFNs are coiled onto themselves the mode propagating in the wire interferes with itself to give a resonator. In contrast with the majority of high-Q resonators manufactured by other means, the OFN microresonator does not have major issues with input-output coupling and presents a completely integrated fiberized solution. OFNs can be used to manufacture loop and coil resonators with Q factors that, although still far from the predicted value of 10. The input-output pigtails play a major role in shaping the resonator response and can be used to maximize the Q factor over a wide range of coupling parameters. Finally, temporal stability and robustness issues are discussed, and a solution to optical degradation issues is presented.