O
Olga Ermakova
Researcher at Heidelberg University
Publications - 34
Citations - 1071
Olga Ermakova is an academic researcher from Heidelberg University. The author has contributed to research in topics: Stem cell & Gene. The author has an hindex of 14, co-authored 31 publications receiving 878 citations. Previous affiliations of Olga Ermakova include Harvard University & University of Alabama at Birmingham.
Papers
More filters
Journal ArticleDOI
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.
Philipp S. Hoppe,Michael Schwarzfischer,Dirk Loeffler,Konstantinos D. Kokkaliaris,Oliver Hilsenbeck,Nadine Moritz,Max Endele,Adam Filipczyk,Adriana Gambardella,Nouraiz Ahmed,Martin Etzrodt,Daniel L. Coutu,Michael A. Rieger,Carsten Marr,Michael Strasser,Bernhard Schauberger,Ingo Burtscher,Olga Ermakova,Antje Bürger,Heiko Lickert,Claus Nerlov,Claus Nerlov,Fabian J. Theis,Timm Schroeder +23 more
TL;DR: The findings suggest that these transcription factors are only executing and reinforcing lineage choice once made, challenging the current prevailing model of early myeloid lineage choice.
Journal ArticleDOI
WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis
Yanfei Ma,Andrej Miotk,Zoran Sutikovic,Olga Ermakova,Christian Wenzl,Anna Medzihradszky,Christophe Gaillochet,Joachim Forner,Gözde Utan,Klaus Brackmann,Carlos S. Galvan-Ampudia,Teva Vernoux,Thomas Greb,Jan U. Lohmann +13 more
TL;DR: It is shown that rheostatic control of auxin response by the WUSCHEL transcription factor maintains stem cells by conferring resistance to auxin mediated differentiation.
Journal ArticleDOI
C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation.
Rodolphe G. Lopez,Susana García-Silva,Susan J. Moore,Oksana Bereshchenko,Ana Belén Martínez-Cruz,Olga Ermakova,Elke Kurz,Jesús M. Paramio,Claus Nerlov,Claus Nerlov +9 more
TL;DR: C/EBPs, therefore, couple basal keratinocyte cell cycle exit to commitment to differentiation through E2F repression and DNA binding, respectively, and may act to restrict the epidermal stem cell compartment.
Journal ArticleDOI
Replication and subnuclear location dynamics of the immunoglobulin heavy-chain locus in B-lineage cells.
TL;DR: Timing data and the direction of replication fork movement indicate that replication of the transition region occurs by a single replication fork, as previously described for MEL cells.
Journal ArticleDOI
PU.1 is not strictly required for B cell development and its absence induces a B-2 to B-1 cell switch
Min Ye,Olga Ermakova,Thomas Graf +2 more
TL;DR: The unexpected outgrowth of B lineage cells from PU.1−/− fetal liver cultures is described, and it is found that B-2 cells express substantially morePU.1 than B-1 cells, which is consistent with the idea that maintenance of the B- 2 cell phenotype requires relatively high levels of PU.