Olga V. Kalinina

TL;DR: It is shown that recombination may play a role in the evolution of Hepatitis C virus (HCV), and Recombination between HCV genotypes must now be considered in the classification, laboratory diagnosis, and treatment of HCV infection.

TL;DR: This “simple” organism makes extensive use of noncoding RNAs and has exon- and intron-like structure within transcriptional operons that allows complex gene regulation resembling that of eukaryotes, and Reconstruction of a bacterial metabolic network reveals strategies for metabolic control with a genome of reduced size.

TL;DR: A method for automated selection of residues that determine the functional specificity of proteins with a common general function (the specificity‐determining positions [SDP] prediction method), which directly takes into account nonuniformity of amino acid substitution frequencies.

TL;DR: It is shown that lipoprotein lipase, targeting triglyceride‐rich lipoproteins to the liver, mediates binding and internalization of HCV to different types of cells, acting as a bridge between virus‐associated lipoproduins and cell surface heparan sulfate proteoglycans.

TL;DR: SDPpred (Specificity Determining Position prediction) is a tool for prediction of residues in protein sequences that determine the proteins' functional specificity for analysis of protein families whose members have biochemically similar but not identical interaction partners.