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Olof Beck

Researcher at Karolinska Institutet

Publications -  322
Citations -  10460

Olof Beck is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: High-performance liquid chromatography & Ethyl glucuronide. The author has an hindex of 54, co-authored 312 publications receiving 9417 citations. Previous affiliations of Olof Beck include Karolinska University Hospital & University of Stuttgart.

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Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification.

TL;DR: During alcohol detoxification, EtG and EtS remained detectable in urine for several days and the detection times showed wide inter-individual variations, also after adjusting values for urine dilution and to the estimated times for a completed ethanol elimination.
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Comparison of urinary excretion characteristics of ethanol and ethyl glucuronide.

TL;DR: It was demonstrated that EtG remains detectable in the urine for many hours after the ethanol itself has been eliminated, and it was possible to lower the concentration of EtG by drinking large amounts of water prior to voiding, whereas this strategy did not influence the EtG/creatinine ratio or the concentrate of ethanol.
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Naltrexone for the Treatment of Amphetamine Dependence: A Randomized, Placebo-Controlled Trial

TL;DR: The main outcome measure was abstinence from amphetamine use, as indicated by the total number of negative amphetamine urine samples during 12 weeks of treatment, and survival analyses showed that the treatment groups differed in rate of continuous abstinence, in both the intention-to-treat and completer samples, in favor of naltrexone treatment.
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Ethyl Sulfate: A Metabolite of Ethanol in Humans and a Potential Biomarker of Acute Alcohol Intake

TL;DR: The present results confirm that sulfate conjugation is a normal but minor metabolic pathway for ethanol in humans, and EtS a common constituent in the urine after alcohol intake, and indicated that the concurrent determination of EtS and EtG will improve sensitivity, when being used as biomarkers of recent drinking.
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Marijuana impairs growth in mid-gestation fetuses.

TL;DR: Evidence is provided of a negative impact of prenatal marijuana exposure on the mid-gestational fetal growth even when adjusting for maternal use of other substances well known to impair fetal development.