Showing papers by "Osama M. Mukdadi published in 2005"

Advantages in using multifrequency excitation of contrast microbubbles for enhancing echo particle image velocimetry techniques: initial numerical studies using rectangular and triangular waves.

Abstract: Accurate measurement of velocity profiles, multiple velocity vectors and local shear stress in arteries is very important for a variety of cardiovascular diseases. We have recently developed an ultrasound based velocimetry technique, termed echo particle image velocimetry (echo PIV). This method takes advantage of the nonlinear backscatter characteristics of ultrasound contrast microbubbles when exposed to certain ultrasonic forcing conditions. Preliminary in vitro, animal and clinical studies have shown significant promise of this method for measuring multiple velocity components with good temporal (up to 2 ms) and spatial (<1 mm) resolution. However, there is still difficulty in maximizing the nonlinearity of bubble backscatter using conventional Gaussian-pulse excitation techniques because: (1) significant harmonic components may not be produced at modest pressure amplitudes; and (2) the higher incident pressure amplitudes required to induce nonlinear behavior may cause bubble destruction. We present here a potential solution to this problem through the use of multifrequency excitation, where rectangular and triangular pulses with four harmonics are used to drive the bubble. The nonlinear behavior of the microbubble, as well as fragility and backscatter, were studied through numerical modeling via a modified Rayleigh-Plesset equation. Results show that the rectangular wave is effective in improving the visibility of microbubbles, with effective scattering cross-section area significantly higher (up to 35 times) than the widely-used Gaussian waveform. However, velocity and acceleration analysis of the bubble wall shows that the rectangular wave may threaten bubble stability. Due to lower wall velocity and acceleration, the triangular wave should decrease the potential for bubble destruction yet maintain relatively high second harmonic backscatter components. The impact of higher harmonics was studied by examining backscatter differences from incident rectangular and triangular pulses with four and two harmonics. Results indicate that a two-frequency excitation (which may be easier to implement practically) may be sufficient to induce nonlinear behavior of the microbubbles at modest incident pressures. These predictions provide support for the use of multifrequency driving to enhance echo PIV applications.

Laser-Generated Thermoelastic Waves in an Anisotropic Infinite Plate: FEM Analysis

Abstract: In recent years, the study of thermoelastic waves generated by focused laser beams has been undertaken by several researchers because the technique provides a means for noncontact generation of ultrasonic waves. Laser-generated ultrasonic waves have diverse applications ranging from material characterization to nondestructive testing of defects. Transient ultrasonic guided waves generated in an anisotropic infinite plate by a pulsed laser beam are investigated in this study. A semi-analytical finite element method (SAFEM) is adopted for this purpose. In this method, the plate is divided into parallel layers through its thickness and the displacement and temperature in each layer are approximated by quadratic polynomials in the thickness direction (z). They are assumed to be continuous functions of time and in-plane cartesian coordinates (x, y). Transient response is calculated using Fourier transformations in time and space variables (x, y). The analysis technique is applicable to a generally ani...

Acoustic-phonon dispersion in nanowires

Abstract: We study phonon dispersion in layered prismatic nanowires that can have an arbitrary cross-sectional geometry. We calculate phonon dispersion using a hybrid analytical/numerical approach that models propagation along the wire analytically, but deformation in the plane of the cross section using the finite element method. In our results we consider only two layers, but the calculational approach is applicable to multiple layers.