scispace - formally typeset
Search or ask a question
Author

Osama M. Mukdadi

Bio: Osama M. Mukdadi is an academic researcher from West Virginia University. The author has contributed to research in topics: Ultrasonic sensor & Dispersion (water waves). The author has an hindex of 14, co-authored 58 publications receiving 690 citations. Previous affiliations of Osama M. Mukdadi include Khalifa University & Office of Technology Transfer.


Papers
More filters
Patent
14 Mar 2013
TL;DR: In this paper, a dual modality probe having both a positron emission tomography sensor and a ultrasound sensor is presented, and a method for evaluating a target organ of a patient utilizing the probe and imaging system, and performing a biopsy of the organ is disclosed.
Abstract: A dual modality probe is disclosed having both a positron emission tomography sensor and a ultrasound sensor. A dual imaging system is provided having the probe and at least one external positron emission tomography detector and a data acquisition computer system for collecting data simultaneously from said positron emission sensor and said ultrasound sensor of said probe and said positron emission tomography detector. A method for evaluating a target organ of a patient utilizing the probe and imaging system, and performing a biopsy of the organ is disclosed.

7 citations

Journal ArticleDOI
TL;DR: A semi-analytical finite element method in which the deformation of the cross section is modeled by two-dimensional finite elements and analytical representation of propagating waves along the long dimension of the plate is used in this paper.
Abstract: Ultrasonic guided waves in a layered elastic plate of rectangular cross section (finite width and thickness) are studied in this paper. A semi-analytical finite element method in which the deformation of the cross sectionis modeled by two-dimensional finite elements and analytical representation of propagating waves along the long dimension of the plate is used. The method is applicable to an arbitrary number of layers of anisotropic properties and is similar to that used earlier to study guided waves in layered anisotropic plates of infinite width. Numerical results are presented for acoustic phonon modes of quasi-one-dimensional (QID) wires. For homogeneous wires, these agree well with recently reported results for dispersion of these modes.

7 citations

Patent
18 Feb 2010
TL;DR: In this paper, a transducer is configured to transmit a series of ultrasonic signals at a plurality of corresponding locations along a jaw and receive a number of echo signals, where each echo signal data corresponds to one of the plurality of transducers position.
Abstract: Disclosed are various embodiments for echoperiodontal imaging. In one embodiment, a system includes a transducer configured to transmit a series of ultrasonic signals at a plurality of corresponding locations along a jaw and receive a plurality of echo signals; and an imaging system controller configured to obtain a plurality of echo signal data and a plurality of transducer positions, where each echo signal data corresponds to one of the plurality of transducer position. In another embodiment, a method includes transmitting a series of ultrasonic signals at a plurality of corresponding locations along a jaw; receiving a plurality of echo signals; obtaining a plurality of echo signal data and a plurality of corresponding transducer positions; and reconstruct image data of a portion of the jaw for display on a display device based upon the obtained echo signal data and corresponding transducer positions.

6 citations

Journal ArticleDOI
TL;DR: An approximate virtual model is designed that includes the smooth, cylindrical dental implant and alveolar bone and loaded with a compressive occlusal force that is applied at the top of the implant platform to provide biomechanical explanations for causes of bone loss around the dental implant after osseointegration.
Abstract: Since the advent of osteointegrated implantology and its precepts issued by the Swedish School, assessment of peri-implant bone loss criteria has often been debated by professionals in this field. Long-term success of dental implants is highly reliant on structural and functional osseointegration between implant and surrounding intraoral tissues. In this context, the current study aims to provide biomechanical explanations for causes of bone loss around the dental implant after osseointegration by computational analysis, using a three-dimensional finite-element (FE) method. We design an approximate virtual model that includes the smooth, cylindrical dental implant and alveolar bone. We use SolidWorks software and export to ABAQUS for computational stress analysis at the bone-implant interface. The numerical model is created and loaded with a compressive occlusal force that is applied at the top of the implant platform. We thoroughly investigate the generated FE results and stress responses of the bone-implant system. The developed model is extremely useful for indicating biomechanical phenomena in the bone-implant interface that play a key part in bone loss around the dental implant. In addition, obtained results tend to deliver an improved understanding to designers in the biomedical engineering field and in dentistry.

6 citations

Journal ArticleDOI
TL;DR: The findings showed that decayed single-rooted teeth are more vulnerable to apical root resorption than healthy teeth and can be implemented to investigate the effectiveness of new advanced restorative materials and protocols.
Abstract: The aim of this study was to investigate the effect of dental caries on the stability of the periodontal system. This study presents a numerical analysis performed with three-dimensional (3D) finite element (FE) method to evaluate stresses in the bone surrounding the tooth with dynamic mastication combined loadings. In this work, we present a comparative study on infected and healthy periodontal systems. The infected tooth was modeled and a caries defect was introduced to the tooth coronal part. The infected tooth was evaluated and equivalent von Mises interface stress values were obtained for comparison with the ones exhibited by the healthy tooth. Our results by 3D FE analysis indicated that maximum stresses occurred primarily at the cervical level of root and alveolar bone. In the cortical bone, the stress value was greater in infected system (21.641 MPa) than in healthy system (15.752 MPa), i.e., a 37.4% increase. However, in the trabecular bone we observed only 1.6% increase in the equivalent stress values for the infected tooth model. Stress concentration at the cervical level may cause abnormal bone remodeling or bone loss, resulting loss of tooth attachment or bone damage. Our findings showed that decayed single-rooted teeth are more vulnerable to apical root resorption than healthy teeth. The numerical method presented in this study not only can aid the elucidation of the biomechanics of teeth infected by caries but also can be implemented to investigate the effectiveness of new advanced restorative materials and protocols.

5 citations


Cited by
More filters
Journal ArticleDOI
TL;DR: The results of the analyses suggest that disease progression to distant sites does not occur exclusively via the axillary lymph nodes, but rather that lymph node status serves as an indicator of the tumor's ability to spread.
Abstract: Two of the most important prognostic indicators for breast cancer are tumor size and extent of axillary lymph node involvement. Data on 24,740 cases recorded in the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute were used to evaluate the breast cancer survival experience in a representative sample of women from the United States. Actuarial (life table) methods were used to investigate the 5-year relative survival rates in cases with known operative/pathologic axillary lymph node status and primary tumor diameter. Survival rates varied from 45.5% for tumor diameters equal to or greater than 5 cm with positive axillary nodes to 96.3% for tumors less than 2 cm and with no involved nodes. The relation between tumor size and lymph node status was investigated in detail. Tumor diameter and lymph node status were found to act as independent but additive prognostic indicators. As tumor size increased, survival decreased regardless of lymph node status; and as lymph node involvement increased, survival status also decreased regardless of tumor size. A linear relation was found between tumor diameter and the percent of cases with positive lymph node involvement. The results of our analyses suggest that disease progression to distant sites does not occur exclusively via the axillary lymph nodes, but rather that lymph node status serves as an indicator of the tumor's ability to spread.

960 citations

Journal ArticleDOI
B.B. Bauer1
01 Apr 1963

897 citations

Proceedings ArticleDOI
TL;DR: In this article, a semi-analytical finite element (SAFE) method for modeling wave propagation in waveguides of arbitrary cross-section is proposed, and the dispersive solutions are obtained in terms of phase velocity, group velocity, energy velocity, attenuation and cross-sectional mode shapes.

534 citations

Journal ArticleDOI
TL;DR: This manuscript reviews the development and application of nanoparticles and their future potential to advance current and emerging clinical bioimaging techniques, with a focus on solid, phase-separated materials, for example metals and metal oxides.
Abstract: Nanoparticle-based contrast agents are quickly becoming valuable and potentially transformative tools for enhancing medical diagnostics for a wide range of in-vivo imaging modalities. Compared with conventional molecular-scale contrast agents, nanoparticles (NPs) promise improved abilities for in-vivo detection and potentially enhanced targeting efficiencies through longer engineered circulation times, designed clearance pathways, and multimeric binding capacities. However, NP contrast agents are not without issues. Difficulties in minimizing batch-to-batch variations and problems with identifying and characterizing key physicochemical properties that define the in-vivo fate and transport of NPs are significant barriers to the introduction of new NP materials as clinical contrast agents. This manuscript reviews the development and application of nanoparticles and their future potential to advance current and emerging clinical bioimaging techniques. A focus is placed on the application of solid, phase-separated materials, for example metals and metal oxides, and their specific application as contrast agents for in-vivo near-infrared fluorescence (NIRF) imaging, magnetic resonance imaging (MRI), positron emission tomography (PET), computed tomography (CT), ultrasound (US), and photoacoustic imaging (PAI). Clinical and preclinical applications of NPs are identified for a broad spectrum of imaging applications, with commentaries on the future promise of these materials. Emerging technologies, for example multifunctional and theranostic NPs, and their potential for clinical advances are also discussed.

441 citations