Author
P. Bryan Hudson
Bio: P. Bryan Hudson is an academic researcher from University of Kansas. The author has contributed to research in topics: Bibenzyl & Amorpha fruticosa. The author has an hindex of 1, co-authored 2 publications receiving 72 citations.
Topics: Bibenzyl, Amorpha fruticosa, Synthon
Papers
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TL;DR: Bioassay directed fractionation of the waxy fractions derived from the fruit of Amorpha fruticosa resulted in the isolation of amorfrutin A and B, active new antimicrobial agents, which were found to be new bibenzyl metabolites.
76 citations
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TL;DR: The integrated inventory of these compounds and their biological macromolecular end-points highlights the opportunities that phytocannabinoids offer to access desirable drug-like space beyond the one associated to the narcotic target CB1.
507 citations
TL;DR: A new species, Mesorhizobium amorphae, is proposed for the majority of the isolates, which belonged to a moderately slow- to slow-growing, acid-producing group based upon their distinct phylogenetic position, their unique electrophoretic type, their low DNA homology, and their distinct phenotypic features.
Abstract: Fifty-five Chinese isolates from nodules of Amorpha fruticosa were characterized and compared with the type strains of the species and genera of bacteria which form nitrogen-fixing symbioses with leguminous host plants. A polyphasic approach, which included RFLP of PCR-amplified 16S rRNA genes, multilocus enzyme electrophoresis (MLEE), DNA-DNA hybridization, 16S rRNA gene sequencing, electrophoretic plasmid profiles, cross-nodulation and a phenotypic study, was used in the comparative analysis. The isolates originated from several different sites in China and they varied in their phenotypic and genetic characteristics. The majority of the isolates had moderate to slow growth rates, produced acid on YMA and harboured a 930 kb symbiotic plasmid (pSym). Five different RFLP patterns were identified among the 16S rRNA genes of all the isolates. Isolates grouped by PCR-RFLP of the 16S rRNA genes were also separated into groups by variation in MLEE profiles and by DNA-DNA hybridization. A representative isolate from each of these DNA homology groups had a separate position in a phylogenetic tree as determine from sequencing analysis of the 16S rRNA genes. A new species, Mesorhizobium amorphae, is proposed for the majority of the isolates, which belonged to a moderately slow- to slow-growing, acid-producing group based upon their distinct phylogenetic position, their unique electrophoretic type, their low DNA homology with reference strains representing the species within the genus Mesorhizobium and their distinct phenotypic features. Strain ACCC 19665 was chosen as the type strain for M. amorphae sp. nov.
202 citations
01 Jan 1982
TL;DR: It is the major object of this review to present the presently known naturally occurring terpenoids and aromatic compounds of the Hepaticae.
Abstract: It is the major object of this review to present the presently known naturally occurring terpenoids and aromatic compounds of the Hepaticae. Furthermore, the biological activity of the isolated compounds and chemosystematics of the Hepaticae are summarized.
161 citations
TL;DR: In this paper, three new bibenzyls and two dihydrophenanthrenes, which exhibit antimicrobial activity, were isolated from tubers of Bletilla striata.
112 citations
01 Jan 1982
TL;DR: In this article, the presently known naturally occurring terpenoids and aromatic compounds of the Hepaticae are reviewed and the biological activity of isolated compounds and chemosystematics of the isolated compounds are summarized.
Abstract: It is the major object of this review to present the presently known naturally occurring terpenoids and aromatic compounds of the Hepaticae. Furthermore, the biological activity of the isolated compounds and chemosystematics of the Hepaticae are summarized.
105 citations