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P. de Wildt

Bio: P. de Wildt is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Chlamydomonas & Hypernova. The author has an hindex of 7, co-authored 7 publications receiving 3477 citations.

Papers
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Journal ArticleDOI
15 Oct 1998-Nature
TL;DR: In this paper, the authors reported the discovery of transient optical emission in the error box of the gamma-ray burst GRB980425, the light curve of which was very different from that of previous optical afterglows associated with Gamma-ray bursts.
Abstract: The discovery of afterglows associated with gamma-ray bursts at X-ray, optical and radio wavelengths and the measurement of the redshifts of some of these events has established that gamma-ray bursts lie at extreme distances, making them the most powerful photon-emitters known in the Universe. Here we report the discovery of transient optical emission in the error box of the gamma-ray burst GRB980425, the light curve of which was very different from that of previous optical afterglows associated with gamma-ray bursts. The optical transient is located in a spiral arm of the galaxy ESO 184-GS2, which has a redshift velocity of only 2,550 km/ s. Its optical spectrum and location indicate that it is a very luminous supernova, which has been identified as SN1998bw. If this supernova and GRB980425 are indeed associated, the energy radiated in gamma-rays is at least four orders of magnitude less than in other gamma-ray bursts, although its appearance was otherwise unremarkable: this indicates that very different mechanisms can give rise to gamma-ray bursts. But independent of this association, the supernova is itself unusual, exhibiting an unusual light curve at radio wavelengths that requires that the gas emitting the radio photons be expanding relativistically.

1,823 citations

Journal ArticleDOI
TL;DR: In this article, the authors reported the discovery of an optical transient, in the BeppoSAX Wide Field Camera error box of GRB980425, which occurred within about a day of the gamma-ray burst.
Abstract: The discovery of X-ray, optical and radio afterglows of gamma-ray bursts (GRBs) and the measurements of the distances to some of them have established that these events come from Gpc distances and are the most powerful photon emitters known in the Universe, with peak luminosities up to 10^52 erg/s. We here report the discovery of an optical transient, in the BeppoSAX Wide Field Camera error box of GRB980425, which occurred within about a day of the gamma-ray burst. Its optical light curve, spectrum and location in a spiral arm of the galaxy ESO 184-G82, at a redshift z = 0.0085, show that the transient is a very luminous type Ic supernova, SN1998bw. The peculiar nature of SN1998bw is emphasized by its extraordinary radio properties which require that the radio emitter expand at relativistical speed. Since SN1998bw is very different from all previously observed afterglows of GRBs, our discovery raises the possibility that very different mechanisms may give rise to GRBs, which differ little in their gamma-ray properties.

1,708 citations

Journal ArticleDOI
01 Apr 1986-Planta
TL;DR: Evidence is presented which supports the concept of a functional membrane barrier in the transition zone at the base of each flagellum of Chlamydomonas eugametos gametes and for the existence of a pool of agglutination factors within the cell bodies but not on the outer surface of the cells.
Abstract: Evidence is presented which supports the concept of a functional membrane barrier in the transition zone at the base of each flagellum of Chlamydomonas eugametos gametes. This makes it unlikely that agglutination factors present on the surface of the cell body can diffuse or be transported to the flagellar membrane. The evidence is as follows: 1) The glycoprotein composition of the flagellar membrane is very different to that of the cell-body plasma membrane. 2) The flagella of gametes treated with cycloheximide, tunicamycin or α, α′-dipyridyl become non-agglutinable but the source of agglutination factors on the cell body is not affected. 3) Even under natural conditions when the flagella are non-agglutinable, for example in vis-a-vis pairs or in appropriate cell strains that are non-agglutinable in the dark, the cell bodies maintain the normal complement of active agglutinins. 4) When flagella of living cells are labeled with antibodies bound to fluorescein, the label does not diffuse onto the cell-body surface. 5) When gametes fuse to form vis-a-vis pairs, the original mating-type-specific antigenicity of each cell body is slowly lost (probably due to the antigens diffusing over both cell bodies), while the specific antigenicity of the flagellar surface is maintained. Even when the flagella of vis-a-vis pairs are regenerated from cell bodies with mixed antigenicity, the antigenicity of the flagella remains matingtype-specific. 6) Evidence is presented for the existence of a pool of agglutination factors within the cell bodies but not on the outer surface of the cells.

69 citations

Journal ArticleDOI
01 Feb 1992-Planta
TL;DR: From the effect of ethanol on the 32P-labelling of polyphosphoinositides, it is concluded that the synthesis of these lipids is stimulated, and this effect, coupled to a rise in intracellular calcium concentration, could explain gamete activation.
Abstract: Alcohols induce mating-structure activation in Chlamydomonas eugametos gametes. From the effect of ethanol on the 32P-labelling of polyphosphoinositides, we conclude that the synthesis of these lipids is stimulated. Biologically inactive concentrations of ethanol (<6%) had no effect on synthesis, but 6–8% ethanol stimulated synthesis for upto 60 min. The 32P incorporated into polyphosphoinositides and phosphatidic acid during ethanol treatment was readily chased out when 1 mM unlabelled Na3PO4 was added. Using a binding assay for inositol 1,4,5-trisphosphate, we show that the production of this phospholipid constituent is dramatically increased after ethanol treatment. This effect, coupled to a rise in intracellular calcium concentration, could explain gamete activation. The significance of these results in explaining other ethanol-induced phenomena in algae is discussed.

30 citations

Journal ArticleDOI
TL;DR: It is shown, by immunofluorescence studies using anti-WGA and an agglutinin- specific monoclonal antibody (mAb 66.3), that WGA induces the redistribution of agglUTinin to the flagellar tips of mt- gametes, and concludes that each agglutanin is associated with a WGA-binding glycoprotein.
Abstract: Species-specific binding between the flagellar surfaces of mating types plus and minus (mt+ and mt-) gametes of Chlamydomonas eugametos is mediated by mating type-specific agglutinins. Their interaction triggers several mating responses that are necessary for cell fusion, such as flagellar twitching, flagellar tip activation, redistribution of agglutinin molecules to the flagellar tip (tipping), and mating structure activation. Earlier, we reported that a monoclonal antibody (mAb 66.3) can induce mating reactions by cross-linking the agglutinins (Homan, W. L., A. Musgrave, H. de Nobel, R. Wagter, A. H. J. Kolk, D. de Wit, and H. van den Ende. 1988. J. Cell Biol. 107:177-189). Here we report that the lectin wheat germ agglutinin (WGA), which does not bind to the agglutinins, can also invoke all these mating reactions. We show, by immunofluorescence studies using anti-WGA and an agglutinin-specific monoclonal antibody (mAb 66.3), that WGA induces the redistribution of agglutinin to the flagellar tips of mt- gametes. Vice versa, when agglutinin tipping is induced by mAb 66.3, the WGA-binding glycoproteins are also tipped. Under the same conditions, the major flagellar glycoproteins are not redistributed, indicating that membrane transport is limited to a few components. We conclude that each agglutinin is associated with a WGA-binding glycoprotein. When cells lacking agglutinin or cells possessing inactive agglutinins are treated with WGA, mating responses are again elicited. The data suggest that clustering of agglutinin-containing complexes results in the production of intracellular signals, such as cAMP, and the coupling of the complex to a force generating system. In nature, the complexes are clustered via the agglutinins, but artificially they can be clustered by lectins or antibodies directed against other proteins in the complex.

29 citations


Cited by
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Journal ArticleDOI
20 Aug 2004
TL;DR: The Swift mission as discussed by the authors is a multi-wavelength observatory for gamma-ray burst (GRB) astronomy, which is a first-of-its-kind autonomous rapid-slewing satellite for transient astronomy and pioneers the way for future rapid-reaction and multiwavelength missions.
Abstract: The Swift mission, scheduled for launch in 2004, is a multiwavelength observatory for gamma-ray burst (GRB) astronomy. It is a first-of-its-kind autonomous rapid-slewing satellite for transient astronomy and pioneers the way for future rapid-reaction and multiwavelength missions. It will be far more powerful than any previous GRB mission, observing more than 100 bursts yr � 1 and performing detailed X-ray and UV/optical afterglow observations spanning timescales from 1 minute to several days after the burst. The objectives are to (1) determine the origin of GRBs, (2) classify GRBs and search for new types, (3) study the interaction of the ultrarelativistic outflows of GRBs with their surrounding medium, and (4) use GRBs to study the early universe out to z >10. The mission is being developed by a NASA-led international collaboration. It will carry three instruments: a newgeneration wide-field gamma-ray (15‐150 keV) detector that will detect bursts, calculate 1 0 ‐4 0 positions, and trigger autonomous spacecraft slews; a narrow-field X-ray telescope that will give 5 00 positions and perform spectroscopy in the 0.2‐10 keV band; and a narrow-field UV/optical telescope that will operate in the 170‐ 600 nm band and provide 0B3 positions and optical finding charts. Redshift determinations will be made for most bursts. In addition to the primary GRB science, the mission will perform a hard X-ray survey to a sensitivity of � 1m crab (� 2;10 � 11 ergs cm � 2 s � 1 in the 15‐150 keV band), more than an order of magnitude better than HEAO 1 A-4. A flexible data and operations system will allow rapid follow-up observations of all types of

3,753 citations

Journal ArticleDOI
B. P. Abbott1, Richard J. Abbott1, T. D. Abbott2, Fausto Acernese3  +1195 moreInstitutions (139)
TL;DR: In this paper, the authors used the observed time delay of $(+1.74\pm 0.05)\,{\rm{s}}$ between GRB 170817A and GW170817 to constrain the difference between the speed of gravity and speed of light to be between $-3
Abstract: On 2017 August 17, the gravitational-wave event GW170817 was observed by the Advanced LIGO and Virgo detectors, and the gamma-ray burst (GRB) GRB 170817A was observed independently by the Fermi Gamma-ray Burst Monitor, and the Anti-Coincidence Shield for the Spectrometer for the International Gamma-Ray Astrophysics Laboratory. The probability of the near-simultaneous temporal and spatial observation of GRB 170817A and GW170817 occurring by chance is $5.0\times {10}^{-8}$. We therefore confirm binary neutron star mergers as a progenitor of short GRBs. The association of GW170817 and GRB 170817A provides new insight into fundamental physics and the origin of short GRBs. We use the observed time delay of $(+1.74\pm 0.05)\,{\rm{s}}$ between GRB 170817A and GW170817 to: (i) constrain the difference between the speed of gravity and the speed of light to be between $-3\times {10}^{-15}$ and $+7\times {10}^{-16}$ times the speed of light, (ii) place new bounds on the violation of Lorentz invariance, (iii) present a new test of the equivalence principle by constraining the Shapiro delay between gravitational and electromagnetic radiation. We also use the time delay to constrain the size and bulk Lorentz factor of the region emitting the gamma-rays. GRB 170817A is the closest short GRB with a known distance, but is between 2 and 6 orders of magnitude less energetic than other bursts with measured redshift. A new generation of gamma-ray detectors, and subthreshold searches in existing detectors, will be essential to detect similar short bursts at greater distances. Finally, we predict a joint detection rate for the Fermi Gamma-ray Burst Monitor and the Advanced LIGO and Virgo detectors of 0.1–1.4 per year during the 2018–2019 observing run and 0.3–1.7 per year at design sensitivity.

2,633 citations

Journal ArticleDOI
TL;DR: A review of the current theoretical understanding of the physical processes believed to take place in GRB's can be found in this article, where the authors focus on the afterglow itself, the jet break in the light curve, and the optical flash that accompanies the GRB.
Abstract: Gamma-ray bursts (GRB's), short and intense pulses of low-energy $\ensuremath{\gamma}$ rays, have fascinated astronomers and astrophysicists since their unexpected discovery in the late sixties. During the last decade, several space missions---BATSE (Burst and Transient Source Experiment) on the Compton Gamma-Ray Observatory, BeppoSAX and now HETE II (High-Energy Transient Explorer)---together with ground-based optical, infrared, and radio observatories have revolutionized our understanding of GRB's, showing that they are cosmological, that they are accompanied by long-lasting afterglows, and that they are associated with core-collapse supernovae. At the same time a theoretical understanding has emerged in the form of the fireball internal-external shocks model. According to this model GRB's are produced when the kinetic energy of an ultrarelativistic flow is dissipated in internal collisions. The afterglow arises when the flow is slowed down by shocks with the surrounding circumburst matter. This model has had numerous successful predictions, like the predictions of the afterglow itself, of jet breaks in the afterglow light curve, and of the optical flash that accompanies the GRB's. This review focuses on the current theoretical understanding of the physical processes believed to take place in GRB's.

1,800 citations

Journal ArticleDOI
19 Jun 2003-Nature
TL;DR: In this article, the authors reported evidence for a very energetic supernova (a hypernova), temporally and spatially coincident with a gamma-ray burst at redshift z=0.1685.
Abstract: Over the past five years evidence has mounted that long-duration (greater than 2s) gamma-ray bursts (GRBs), the most brilliant of all astronomical explosions, signal the collapse of massive stars in our Universe. This evidence, originally based on the probable association of one unusual GRB with a supernova, now includes the association of GRBs with regions of massive star-formation in distant galaxies, tantalizing evidence of supernova-like light-curve 'bumps' in the optical afterglows of several bursts, and lines of freshly synthesized elements in the spectra of a few X-ray afterglows. These observations support, but do not yet conclusively validate, models based upon the deaths of massive stars, presumably associated with core collapse. Here we report evidence for a very energetic supernova (a hypernova), temporally and spatially coincident with a GRB at redshift z=0.1685. The timing of the supernova indicates that it exploded within a few days of the GRB, strongly suggesting that core-collapse events can give rise to GRBs. Amongst the GRB central engine models proposed to-date, the properties of this supernova thus favour the collapsar model.

1,415 citations

Journal ArticleDOI
TL;DR: In this article, it was shown that most long-duration soft-spectrum gamma-ray bursts are accompanied by massive stellar explosions (GRB-SNe) and that most of the energy in the explosion is contained in nonrelativistic ejecta (producing the supernova) rather than in the relativistic jets responsible for making the burst and its afterglow.
Abstract: Observations show that at least some gamma-ray bursts (GRBs) happen simultaneously with core-collapse supernovae (SNe), thus linking by a common thread nature's two grandest explosions. We review here the growing evidence for and theoretical implications of this association, and conclude that most long-duration soft-spectrum GRBs are accompanied by massive stellar explosions (GRB-SNe). The kinetic energy and luminosity of well-studied GRB-SNe appear to be greater than those of ordinary SNe, but evidence exists, even in a limited sample, for considerable diversity. The existing sample also suggests that most of the energy in the explosion is contained in nonrelativistic ejecta (producing the supernova) rather than in the relativistic jets responsible for making the burst and its afterglow. Neither all SNe, nor even all SNe of Type Ibc produce GRBs. The degree of differential rotation in the collapsing iron core of massive stars when they die may be what makes the difference.

1,389 citations