P. Hirschmann

TL;DR: The presence of not one but three spermatogenesis loci in Yq11 is proposed and that each locus is active during a different phase of male germ cell development.

TL;DR: It is assumed that intrachromosomal recombination events between the two homologous retroviral sequence blocks in proximal Yq11 are probably the causative agents for most of the AZFa microdeletions observed in men with SCO syndrome.

TL;DR: Evidence is presented that not DAZ but SPGYLA is the functional human homologue of Dazla and boule, suggesting that all were encoded by the same gene.

TL;DR: A rapid molecular screening programme has been established for the long arm of the human Y chromosome in Yq11 in order to quickly detect small interstitial deletions in this chromosome region indicative for deletion of AZF gene sequences.

TL;DR: The frequency of AZF mutations in idiopathic sterile males (5-20%) may indicate a need for a general screening programme for its analysis in infertility clinics and indicates that azoospermia is possibly caused by more than one Y gene in Yq11 and the Yq 11 chromatin structure.