Author
P. Lakshmi Reddy
Bio: P. Lakshmi Reddy is an academic researcher from Indian Institute of Chemical Technology. The author has contributed to research in topics: Catalysis & Hydroacylation. The author has an hindex of 4, co-authored 11 publications receiving 64 citations.
Topics: Catalysis, Hydroacylation, Bromide, Isocyanide, Sulfonic acid
Papers
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TL;DR: Iodine is found to be a highly efficient catalyst for the three-component coupling (3CC) of aldehydes, β-naphthol, and 1,3-dimethylbarbituric acid under solvent-free conditions to afford the corresponding 8,10-dimyl-12-aryl-12 H -naphTHo[1′,2′5,6]pyrano[2,3]-d ]pyrimidine-9,11-diones in good yields with high selectivity as discussed by the authors.
37 citations
TL;DR: Microwave-induced cyclocondensation of methyl 2-(acetoxy(phenyl)methyl)acrylate with 2-aminopyridines under catalyst and solvent-free conditions has been achieved for a rapid synthesis of 3-substituted-2 H -pyrido[1,2- a ]pyrimidin-2-ones in good yields with high selectivity in short reaction times as discussed by the authors.
12 citations
TL;DR: In this article, an improved method was developed for the hydroacylation of enones with aldehydes employing bis-5-(2-hydroxyethyl)-1,3-thiazolium bromide/Et3N system to afford the corresponding 1,4-diketones in good yields.
9 citations
TL;DR: A three-component, four center Ugi reaction of 3-(1-(2-aminophenyl)-5-phenyl-1H-pyrrol-2-yl)propanoic acid with aromatic aldehyde and t-butyl isocyanide has been achieved to produce a novel class of N-tertbutyl-2-(6-oxo-11-,phenyl)-7,8-dihydrobenzo[b]pyrolo[1,2-d][1,4]diazacine-
8 citations
TL;DR: In this article, a three-component coupling of indoles, aldehydes, and Nalkylanilines has been achieved using a catalytic amount of cellulose-sulfonic acid under mild reaction conditions to furnish the 3-a...
Abstract: Three-component coupling (3CC) of indoles, aldehydes, and N-alkylanilines has been accomplished using a catalytic amount of cellulose–sulfonic acid under mild reaction conditions to furnish the 3-a...
5 citations
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TL;DR: The synergistic effect of the combined use of MCRs and molecular iodine for the development of new eco-compatible methodologies for organic chemistry is highlighted.
Abstract: The multicomponent reactions (MCRs) consist of two or more synthetic steps which are carried out without isolation of any intermediate thus reducing time, saving money, energy and raw materials. The development of MCRs in the presence of molecular iodine is an efficient approach that meets with the requirements of sustainable chemistry. The aim of this review is to highlight the synergistic effect of the combined use of MCRs and molecular iodine for the development of new eco-compatible methodologies for organic chemistry.
158 citations
TL;DR: Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbcycle-clic compounds and considered as an important building block in organic synthesis as mentioned in this paper.
Abstract: Barbituric acid has been utilized in the design and synthesis of diverse types of heterocyclic and carbocyclic compounds and considered as an important building block in organic synthesis. There is a wide range of multicomponent reactions that include barbituric acid as starting material. This article aims to review the chemistry of barbituric acids employed in the design and synthesis of different types of compounds during the period from 2011 to 2015.
72 citations
67 citations
TL;DR: In this article, a simple, efficient, and green practical approach to 1H-pyrazolo[1,2-b]phthalazine-5,10-diones from phthalhydrazide, aldehydes, and malononitrile/ethyl cyanoacetate has been developed that uses inexpensive and readily available InCl3 as a catalyst in solvent-free one-pot three-component cyclo condensation reaction.
49 citations
TL;DR: In this article, an efficient one pot multi-component sequential reaction of phenyl hydrazine, malanonitrile and a diverse range of aldehydes to afford highly functionalised pyrazoles is reported.
Abstract: An efficient one pot multi-component sequential reaction of phenyl hydrazine, malanonitrile and a diverse range of aldehydes to afford highly functionalised pyrazoles is reported. The reaction proceeds in water using molecular iodine as a catalyst, with no by-product formation, and involves simple operation requiring no column chromatography. Thus, this protocol fulfils all of the criteria that define green chemistry.
47 citations