P
P. Rajaguru
Researcher at Anna University
Publications - 42
Citations - 1791
P. Rajaguru is an academic researcher from Anna University. The author has contributed to research in topics: Oxidative stress & Genotoxicity. The author has an hindex of 22, co-authored 40 publications receiving 1533 citations. Previous affiliations of P. Rajaguru include Bharathidasan University & Bharathidasan Institute of Technology.
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Biodegradation of azo dyes in a sequential anaerobic-aerobic system.
TL;DR: A sequential anaerobic–aerobic treatment process based on mixed culture of bacteria isolated from textile dye effluent-contaminated soil was used to degrade sulfonated azo dyes Orange G (OG), Amido black 10B (AB), Direct red 4BS (DR) and Congo red (CR).
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The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes.
Elango Bhakkiyalakshmi,Dornadula Sireesh,P. Rajaguru,Ramasamy Paulmurugan,Kunka Mohanram Ramkumar +4 more
TL;DR: The molecular mechanism behind Nrf2 activation and the impact of NRF2 activators in diabetes and its complications is summarized and identification of small molecule activators of Nrf1/Keap1 pathway remains significant to enhance cellular defense to overcome the burden of oxidative stress related disturbances.
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MicroRNA Regulation of Acute Lung Injury and Acute Respiratory Distress Syndrome
Subbiah Rajasekaran,Dhamotharan Pattarayan,P. Rajaguru,P. S. Sudhakar Gandhi,Rajesh K. Thimmulappa +4 more
TL;DR: A large body of evidence implicating miRNAs and their target molecules in ALI/ARDS originating largely from studies using animal and cell culture model systems is summarized, focusing on the involvement ofmiRNAs in macrophage polarization, which play a critical role in regulating the pathogenesis of ALI.
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Genotoxicity evaluation of polluted ground water in human peripheral blood lymphocytes using the comet assay
TL;DR: The genotoxicity experiments with the ground water collected from an area under the influence of textile dyeing and bleaching industries in Tirupur, Tamilnadu, India demonstrate the application of the comet assay in environmental monitoring studies.
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Therapeutic potential of pterostilbene against pancreatic beta‐cell apoptosis mediated through Nrf2
Elango Bhakkiyalakshmi,Devibalan Shalini,Thillai V. Sekar,P. Rajaguru,Ramasamy Paulmurugan,Kunka Mohanram Ramkumar,Kunka Mohanram Ramkumar +6 more
TL;DR: For the first time, the protective properties of a naturally available antioxidant, pterostilbene (PTS), against pancreatic beta‐cell apoptosis and the involvement of Nrf2 in its mechanism of action are investigated.