P
P. Tiveron
Researcher at Istituto Superiore di Sanità
Publications - 17
Citations - 715
P. Tiveron is an academic researcher from Istituto Superiore di Sanità. The author has contributed to research in topics: Relative biological effectiveness & Linear energy transfer. The author has an hindex of 11, co-authored 17 publications receiving 682 citations.
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Journal ArticleDOI
RBE- LET relationships for cell inactivation and mutation induced by low energy protons in V79 cells: further results at the LNL facility
Mauro Belli,F. Cera,Roberto Cherubini,M. Dalla Vecchia,A. M. I. Haque,Fiorenza Ianzini,G. Moschini,Orazio Sapora,Giustina Simone,M. A. Tabocchini,P. Tiveron +10 more
TL;DR: The proton RBE-LET relationship for cell inactivation is shifted to lower LET values compared with that for heavier ions, and the RBE for mutation induction increased continuously with LET.
Journal ArticleDOI
Inactivation and Mutation Induction in V79 Cells by Low Energy Protons: Re-evaluation of the Results at the LNL Facility
Mauro Belli,F. Cera,Roberto Cherubini,A. M. I. Haque,F. Ianzini,G. Moschini,Orazio Sapora,Giustina Simone,M. A. Tabocchini,P. Tiveron +9 more
TL;DR: Re-evaluation of the physical parameters for all the proton beams used in previous radiobiological investigations leads to significant changes in the dose-response curves and in the RBE-LET relationships, pointing out that there is a LET range where protons are more effective than alpha-particles.
Journal ArticleDOI
Inactivation of human normal and tumour cells irradiated with low energy protons.
Mauro Belli,Daniela Bettega,P. Calzolari,F. Cera,Roberto Cherubini,M. Dalla Vecchia,Marco Durante,S. Favaretto,G. Gialanella,G. F. Grossi,Renato Marchesini,G. Moschini,A. Piazzola,Gian Luca Poli,Mariagabriella Pugliese,Orazio Sapora,Paola Scampoli,Giustina Simone,Eugenio Sorrentino,M. A. Tabocchini,L. Tallone,P. Tiveron +21 more
TL;DR: RBE for inactivation with high-LET protons increased with the cellular radioresistance to gamma-rays, and a similar trend has been found in studies reported in the literature with He, C, N ions with LET in the range 20-125 keV/microm on human tumour cell lines.
Journal ArticleDOI
DNA DSB induction and rejoining in V79 cells irradiated with light ions : A constant field gel electrophoresis study
Mauro Belli,Roberto Cherubini,M. Dalla Vecchia,Valentina Dini,G. Moschini,Claudia Signoretti,Giustina Simone,M. A. Tabocchini,P. Tiveron +8 more
TL;DR: The hypothesis that complex, less reparable DSB are induced in higher proportion by light ions with respect to gamma-rays and that, for the same ion, increasing LET leads to an increase in this proportion is supported.
Journal ArticleDOI
Inactivation of C3H10T1/2 cells by low energy protons and deuterons.
Daniela Bettega,P. Calzolari,Renato Marchesini,G. Noris Chiorda,A. Piazzolla,L. Tallone,F. Cera,Roberto Cherubini,M. Dalla Vecchia,S. Favaretto,P. Tiveron +10 more
TL;DR: No difference in effectiveness for inactivation of C3H10T1/2 has been found between protons and deuterons at two LET values in the range 10-20 keV/microm and proton RBE values are significantly larger than unity at LET values as low as 11 keV /microm.