P
Pablo Tamayo
Researcher at University of California, San Diego
Publications - 185
Citations - 117545
Pablo Tamayo is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 72, co-authored 177 publications receiving 97318 citations. Previous affiliations of Pablo Tamayo include University of California, Berkeley & Harvard University.
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Proceedings ArticleDOI
Abstract 4368: High-throughput phenotyping of lung cancer somatic mutations
Alice H. Berger,Angela N. Brooks,Xiaoyun Wu,Yashaswi Shrestha,Candace R. Chouinard,Federica Piccioni,Mukta Bagul,Atanas Kamburov,Marcin Imielinski,Larson Hogstrom,Cong Zhu,Xiaoping Yang,Sasha Pantel,Ryo Sakai,Nathan O. Kaplan,David E. Root,Rajiv Narayan,Ted Natoli,David L. Lahr,Itay Tirosh,Pablo Tamayo,Gad Getz,Bang Wong,John G. Doench,Aravind Subramanian,Todd R. Golub,Matthew Meyerson,Jesse S. Boehm +27 more
TL;DR: A new high-throughput approach, expression-based variant impact phenotyping (eVIP), which uses gene expression changes to infer somatic mutation impact, and identified 69% of mutations as impactful whereas 31% appeared functionally neutral.
Journal ArticleDOI
Responses to immunotherapy in hepatocellular carcinoma patients with nonalcoholic steatohepatitis cirrhosis.
TL;DR: There were significantly higher rates of disease progression as the best response to immunotherapy in patients with HCC and NASH Cirrhosis compared to those without NASH cirrhosis.
Journal ArticleDOI
Su.86. Automated High-dimensional Flow Cytometric Data Analysis
Xinli Hu,Saumyadipta Pyne,Elizabeth J. Rossin,Pablo Tamayo,David A. Hafler,Jill P. Mesirov,Philip L. De Jager +6 more
Portraits of breast cancer progression
Gul S. Dalgin,Gabriela Alexe,Gabriela Alexe,Daniel Scanfeld,Pablo Tamayo,Jill P. Mesirov,Shridar Ganesan,Charles DeLisi,Gyan V. Bhanot +8 more
TL;DR: The method identifies an optimum set of genes and divides the samples into stable clusters which correlate with clinical classification into Luminal, Basal-like and Her2+ subtypes, revealing a hierarchical portrait of breast cancer progression.
Journal ArticleDOI
Constellation Map: Downstream visualization and interpretation of gene set enrichment results.
Yan Tan,Yan Tan,Felix Wu,Pablo Tamayo,W. Nicholas Haining,W. Nicholas Haining,Jill P. Mesirov,Jill P. Mesirov +7 more
TL;DR: Constellation Map is presented, a tool to visualize and interpret the results when enrichment analyses yield a long list of significantly enriched gene sets, and identifies commonalities that explain the enrichment of multiple top-scoring gene sets and maps the relationships between them.