P
Páll Melsted
Researcher at University of Iceland
Publications - 81
Citations - 14841
Páll Melsted is an academic researcher from University of Iceland. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 31, co-authored 68 publications receiving 10282 citations. Previous affiliations of Páll Melsted include University of Chicago & Carnegie Mellon University.
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Journal ArticleDOI
Near-optimal probabilistic RNA-seq quantification
TL;DR: Kallisto pseudoaligns reads to a reference, producing a list of transcripts that are compatible with each read while avoiding alignment of individual bases, which removes a major computational bottleneck in RNA-seq analysis.
Journal ArticleDOI
Mash: fast genome and metagenome distance estimation using MinHash.
Brian D. Ondov,Todd J. Treangen,Páll Melsted,Adam B. Mallonee,Nicholas H. Bergman,Sergey Koren,Adam M. Phillippy +6 more
TL;DR: Mash extends the MinHash dimensionality-reduction technique to include a pairwise mutation distance and P value significance test, enabling the efficient clustering and search of massive sequence collections.
Journal ArticleDOI
Spread of SARS-CoV-2 in the Icelandic Population.
Daniel F. Gudbjartsson,Agnar Helgason,Hakon Jonsson,Olafur T. Magnusson,Páll Melsted,Gudmundur L. Norddahl,Jona Saemundsdottir,Asgeir Sigurdsson,Patrick Sulem,Arna B Agustsdottir,Berglind Eiriksdottir,Run Fridriksdottir,Elisabet E Gardarsdottir,Gudmundur Georgsson,Olafia S Gretarsdottir,Kjartan R Gudmundsson,Thora R Gunnarsdottir,Arnaldur Gylfason,Hilma Holm,Brynjar O. Jensson,Aslaug Jonasdottir,Frosti Jonsson,Kamilla S Josefsdottir,Thordur Kristjansson,Droplaug N Magnusdottir,Louise le Roux,Gudrun Sigmundsdottir,Gardar Sveinbjornsson,Kristin E Sveinsdottir,Maney Sveinsdottir,Emil A Thorarensen,Bjarni Thorbjornsson,Arthur Löve,Gisli Masson,Ingileif Jonsdottir,Alma D. Möller,Thorolfur Gudnason,Karl G. Kristinsson,Unnur Thorsteinsdottir,Kari Stefansson +39 more
TL;DR: In a population-based study in Iceland, children under 10 years of age and females had a lower incidence of SARS-CoV-2 infection than adolescents or adults and males and the proportion of infected participants identified through population screening remained stable for the 20-day duration of screening.
Journal ArticleDOI
Differential analysis of RNA-seq incorporating quantification uncertainty.
TL;DR: A method for the differential analysis of gene expression data that utilizes bootstrapping in conjunction with response error linear modeling to decouple biological variance from inferential variance is described.
Journal ArticleDOI
Humoral Immune Response to SARS-CoV-2 in Iceland.
Daniel F. Gudbjartsson,Gudmundur L. Norddahl,Páll Melsted,Kristbjorg Gunnarsdottir,Hilma Holm,Elias Eythorsson,Asgeir O. Arnthorsson,Dadi Helgason,Kristbjorg Bjarnadottir,Ragnar Freyr Ingvarsson,Brynja Thorsteinsdottir,Steinunn Kristjánsdóttir,Kolbrun Birgisdottir,Anna M. Kristinsdottir,Martin I. Sigurdsson,Gudny A. Arnadottir,Erna V. Ivarsdottir,Margret B. Andresdottir,Frosti Jonsson,Arna B Agustsdottir,Jonas Berglund,Berglind Eiriksdottir,Run Fridriksdottir,Elisabet E Gardarsdottir,Magnus Gottfredsson,Olafia S Gretarsdottir,Steinunn Gudmundsdottir,Kjartan R Gudmundsson,Thora R Gunnarsdottir,Arnaldur Gylfason,Agnar Helgason,Brynjar O. Jensson,Aslaug Jonasdottir,Hakon Jonsson,Thordur Kristjansson,Karl G. Kristinsson,Droplaug N Magnusdottir,Olafur T. Magnusson,Lovisa Bjork Olafsdottir,Solvi Rognvaldsson,Louise le Roux,Gudrun Sigmundsdottir,Asgeir Sigurdsson,Gardar Sveinbjornsson,Kristin E Sveinsdottir,Maney Sveinsdottir,Emil A Thorarensen,Bjarni Thorbjornsson,Marianna Thordardottir,Jona Saemundsdottir,S Hjortur Kristjansson,Kamilla S Josefsdottir,Gisli Masson,Gudmundur Georgsson,Mar Kristjansson,Alma D. Möller,Runolfur Palsson,Thorolfur Gudnason,Unnur Thorsteinsdottir,Ingileif Jonsdottir,Patrick Sulem,Kari Stefansson +61 more
TL;DR: The authors' results indicate that antiviral antibodies against SARS-CoV-2 did not decline within 4 months after diagnosis, and antiviral antibody titers assayed by two pan-Ig assays remained on a plateau for the remainder of the study.