P
Pamela M. Hartigan
Researcher at Veterans Health Administration
Publications - 88
Citations - 12420
Pamela M. Hartigan is an academic researcher from Veterans Health Administration. The author has contributed to research in topics: Percutaneous coronary intervention & Coronary artery disease. The author has an hindex of 37, co-authored 87 publications receiving 11651 citations. Previous affiliations of Pamela M. Hartigan include Hartford Hospital & United States Department of Veterans Affairs.
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Journal ArticleDOI
Optimal Medical Therapy with or without PCI for Stable Coronary Disease
William E. Boden,Koon K. Teo,Pamela M. Hartigan,David J. Maron,William J. Kostuk,Merril L. Knudtson,Marcin Dada,Paul Casperson,Crystal L. Harris,Bernard R. Chaitman,Leslee J. Shaw,Gilbert Gosselin,Shah Nawaz,Lawrence M. Title,Gerald T. Gau,Alvin Blaustein,David C. Booth,Eric R. Bates,John A. Spertus,Daniel S. Berman,William S. Weintraub +20 more
TL;DR: As an initial management strategy in patients with stable coronary artery disease, PCI did not reduce the risk of death, myocardial infarction, or other major cardiovascular events when added to optimal medical therapy.
Journal ArticleDOI
Optimal Medical Therapy With or Without Percutaneous Coronary Intervention to Reduce Ischemic Burden Results From the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) Trial Nuclear Substudy
Leslee J. Shaw,Daniel S. Berman,David J. Maron,G.B. John Mancini,Sean W. Hayes,Pamela M. Hartigan,William S. Weintraub,Robert A. O'Rourke,Marcin Dada,John A. Spertus,Bernard R. Chaitman,John D. Friedman,Piotr J. Slomka,Gary V. Heller,Guido Germano,Gilbert Gosselin,Peter B. Berger,William J. Kostuk,Ronald G. Schwartz,Merill L Knudtson,Emir Veledar,Eric R. Bates,Benjamin D. McCallister,Koon K. Teo,William E. Boden +24 more
TL;DR: In COURAGE patients who underwent serial MPS, adding PCI to OMT resulted in greater reduction in ischemia compared with OMT alone, and the findings suggest a treatment target of ≥5% ischemic myocardium reduction with O MT with or without coronary revascularization.
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Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS. Veterans Affairs Cooperative Study Group on AIDS.
William A. O'Brien,Pamela M. Hartigan,David W. Martin,James Esinhart,Andrew Hill,Sharon L. Benoit,Marc Rubin,Michael S. Simberkoff,John D. Hamilton +8 more
TL;DR: Treatment-induced changes in the plasma HIV-1 RNA level and the CD4+ lymphocyte count are valid predictors of the clinical progression of HIV-related disease and can be used to assess the efficacy of zidovudine and possibly other antiretroviral drugs as well.
Journal ArticleDOI
A comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. Veterans Affairs ACME Investigators.
TL;DR: For patients with single-vessel coronary artery disease, PTCA offers earlier and more complete relief of angina than medical therapy and is associated with better performance on the exercise test.
Journal ArticleDOI
Effect of PCI on Quality of Life in Patients with Stable Coronary Disease
William S. Weintraub,John A. Spertus,Paul Kolm,David J. Maron,Zefeng Zhang,Claudine Jurkovitz,Wei Zhang,Pamela M. Hartigan,Cheryl Lewis,Emir Veledar,James M. Bowen,Sandra B. Dunbar,Christi Deaton,Stanley E. Kaufman,Robert A. O'Rourke,Ron Goeree,Paul G. Barnett,Koon K. Teo,William E. Boden +18 more
TL;DR: Among patients with stable angina, both thosetreated with PCI and those treated with optimal medical therapy alone had marked improvements in health status during follow-up, and similar incremental benefits from PCI were seen in some but not all RAND-36 domains.