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Paola Bernabei
Researcher at University of Turin
Publications - 28
Citations - 1801
Paola Bernabei is an academic researcher from University of Turin. The author has contributed to research in topics: T cell & Receptor. The author has an hindex of 18, co-authored 27 publications receiving 1594 citations.
Papers
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in vitro and in vivo
Gabriella Regis,Marita Bosticardo,Laura Conti,Stefania De Angelis,Daniela Boselli,Barbara Tomaino,Paola Bernabei,Mirella Giovarelli,Francesco Novelli +8 more
Journal ArticleDOI
Interferon‐γ receptor 2 expression as the deciding factor in human T, B, and myeloid cell proliferation or death
Paola Bernabei,Eliana M. Coccia,Laura Rigamonti,Marita Bosticardo,Guido Forni,Sidney Pestka,Christopher D. Krause,Angela Battistini,Francesco Novelli +8 more
TL;DR: It is concluded that the surface expression of IFN‐γR2 determines whether a cell stimulated by IFn‐γ undergoes proliferation or apoptosis.
Journal Article
Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis.
Alessandra Allione,Paola Bernabei,Marita Bosticardo,Silvia Ariotti,Guido Forni,Francesco Novelli +5 more
TL;DR: NO is identified as one of the environmental factors that critically govern the response of T cells to IFN-gamma, by inducing the overexpression of IFN -gammaR chains, which decides whether IFn-Gamma promotes cell proliferation or the induction of apoptosis.
Journal Article
Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor.
Francesco Novelli,Paola Bernabei,Laurence Ozmen,Laura Rigamonti,Alessandra Allione,Sidney Pestka,Gianni Garotta,Guido Forni +7 more
TL;DR: A correlation exists between differential expression of the IFN-gamma R beta-chain and the delivery by IFN -gamma of proliferative or apoptotic signals.
Journal Article
Expression and role in apoptosis of the alpha- and beta-chains of the IFN-gamma receptor on human Th1 and Th2 clones.
Francesco Novelli,Mario Milco D'Elios,Paola Bernabei,Laurence Ozmen,Laura Rigamonti,Fabio Almerigogna,Guido Forni,G Del Prete +7 more
TL;DR: Results indicate that activated human Th1 and Th2 lymphocytes express IFN-gammaR alpha- and beta-chains and are both sensitive to signals provided by IFN -gamma, and suggest thatIFN-Gamma is critical for switching off their responses.