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Author

Parinaz Abdollahiyan

Other affiliations: Nanjing Forestry University
Bio: Parinaz Abdollahiyan is an academic researcher from Tabriz University of Medical Sciences. The author has contributed to research in topics: 3D bioprinting & Self-healing hydrogels. The author has an hindex of 4, co-authored 11 publications receiving 52 citations. Previous affiliations of Parinaz Abdollahiyan include Nanjing Forestry University.

Papers
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Journal ArticleDOI
TL;DR: Cutting‐edge developments in hydrogel‐type bioinks are reviewed and the optimum simulation of the zonal stratification in osteochondral and cartilage units is discussed to enhance the printing quality of scaffolds and determine the nurture of cellular morphology.
Abstract: As a milestone in soft and hard tissue engineering, a precise control over the micropatterns of scaffolds has lightened new opportunities for the recapitulation of native body organs through three dimentional (3D) bioprinting approaches. Well-printable bioinks are prerequisites for the bioprinting of tissues/organs where hydrogels play a critical role. Despite the outstanding developments in 3D engineered microstructures, current printer devices suffer from the risk of exposing loaded living agents to mechanical (nozzle-based) and thermal (nozzle-free) stresses. Thus, tuning the rheological, physical, and mechanical properties of hydrogels is a promising solution to address these issues. The relationship between the mechanical characteristics of hydrogels and their printability is important to control printing quality and fidelity. Recent developments in defining this relationship have highlighted the decisive role of main additive manufacturing strategies. These strategies are applied to enhance the printing quality of scaffolds and determine the nurture of cellular morphology. In this regard, it is beneficial to use external and internal stabilization, photocurable biopolymers, and cooling substrates containing the printed scaffolds. The objective of this study is to review cutting-edge developments in hydrogel-type bioinks and discuss the optimum simulation of the zonal stratification in osteochondral and cartilage units.

76 citations

Journal ArticleDOI
TL;DR: In this article, a review has addressed the most recent advances in the tissue engineering of various organs with a focus on the applications of nanomaterials in this field, and the nature of damaged tissues, as well as scaffolds' composition, porous structure, degradability, and biocompatibility are determinant factors for successful tissue engineering.

38 citations

Journal ArticleDOI
TL;DR: This study reviews a brief explanation of the structure, characters, applications, fabrication methods, and future outlooks of stimuli responsive hydrogels in tissue engineering and, in particular, 3D bioprinting.

37 citations

Journal ArticleDOI
TL;DR: In this article, most advanced technical improvements, experiments, and future outlooks of hard tissue engineering are discussed, as well as their relevant additive manufacturing techniques, and a review of 3D bioprinting methods still have some uncertainties.

27 citations

Journal ArticleDOI
TL;DR: In this article, a novel type of highly fluorescent probe for selective Cu2+ detection among 26 types of metal ions which considerably enhance the fluorescence intensity of GQD was presented.
Abstract: This study reports the synthesis of functional graphene quantum dots (GQDs) through the thermal pyrolysis of D-penicillamine (DPA) and citric acid towards water treatment. For the first time, a novel type of highly fluorescent probe for selective Cu2+ detection among 26 types of metal ions which considerably enhance the fluorescence intensity of GQD. Furthermore, the recognition effects can be strengthen addition of amino acids owing to raise the electron density of the system and boos the accumulation profile of the sensing molecules. This simple fluorescent probe was applied for facile metal ions recognition in human urine samples, as well as environmental fluids. The proposed DPA-GQDs supported amino acids respond to Cu2+, Hg2+, and Fe3+, with high sensitivity. The intensity of the fluorescence histogram of this probe significantly diminished in exposure to metal ions such as, Cu(II), Hg(II), and Fe(III). Moreover, in our work, microfluidic paper-based (µPADs) was fabricated through a facile and a cost-effective method. Cu2+ can selectively be recognized by GQD-DPA on the paper-based sensors by naked-eye. The functionalized DPA-GQDs is an excellent alternative to previously reported fluorescent probes for sensing, bio-labeling, and other biological usages in aqueous solution. Its nitrogen and oxygen-rich groups can coordinate with Cu2+ and cause to an apparent fluorescence quenching by the non-radiative electron-transmission. The technique presented in this paper is economical and simple in design, and provides a "mix-and-sense" protocol with no need to chemical- or dye-modifications. Our proposed Cu2+ sensing probe exhibits linear response in the concentrations ranging from 0.001 ppm to 5 ppm, with a lower limit of quantitation (LLOQ) of 0.1 ppm in both environmental fluids, and human urine samples. The enhanced color uniformity, the low instrumental needs of the stamp, and disposability of μPADs enable the application of the suggested paper-based device for the commercial diagnostics biosensor.

19 citations


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Journal ArticleDOI
TL;DR: GO@CoFe2O4 can be a potential candidate to eliminate DCF drug from water with good removal efficiency, high maximum adsorption capacity, and elucidated the role of functional groups on the surface of GO@Co Fe2 O4 in enhancing the adsorbent ofDCF drug.
Abstract: Aquatic contamination of diclofenac (DCF), an emergent non-steroidal anti-inflammatory drug (NSAIDs), can result in adverse effects to many ecosystems through biomagnification. Hence, introducing effective remediation techniques to sequester the pharmaceutical wastes is highly fundamental to prevent their accumulation in the environment. Generally, adsorption has been presented as a green and efficient approach. Herein, we report the characterization and application of the novel magnetic nanocomposite (GO@CoFe2O4) derived from cobalt-based ferrite (CoFe2O4) and graphene oxide (GO) for DCF adsorption. For the optimization procedure, the response surface methodology (RSM) was adopted to investigate the impacts of DCF concentration (1.6–18.4 mg/L), DCF dosage (0.08–0.92 g/L), and solution pH (2.6–9.4) to find the optimum conditions for DCF removal, at 10.5 mg/L, 0.74 g/L, and pH 4, respectively. For the adsorption experiments, the kinetic, isotherm, thermodynamic, and intraparticle diffusion models were systematically studied. Moreover, we have elucidated the role of functional groups on the surface of GO@CoFe2O4 in enhancing the adsorption of DCF drug. With good removal efficiency (up to 86.1%), high maximum adsorption capacity (32.4 mg/g), GO@CoFe2O4 can be a potential candidate to eliminate DCF drug from water.

69 citations

Journal ArticleDOI
TL;DR: This review condense the findings, summarize the improvements that are needed for the use of 3D printing in medicine, as well as plausible methods for creating medicines and medical devices in the future.

47 citations

DOI
24 Jun 2021
TL;DR: In this paper, a review of the 3D bioprinted photo-crosslinkable hydrogel scaffolds for bone and cartilage defect repair is presented, and future perspectives about the development of 3D-bioprinting photo-linkable hyrogels in bone and/or cartilage engineering are discussed.
Abstract: Three-dimensional (3D) bioprinting has become a promising strategy for bone manufacturing, with excellent control over geometry and microarchitectures of the scaffolds. The bioprinting ink for bone and cartilage engineering has thus become the key to developing 3D constructs for bone and cartilage defect repair. Maintaining the balance of cellular viability, drugs or cytokines' function, and mechanical integrity is critical for constructing 3D bone and/or cartilage scaffolds. Photo-crosslinkable hydrogel is one of the most promising materials in tissue engineering; it can respond to light and induce structural or morphological transition. The biocompatibility, easy fabrication, as well as controllable mechanical and degradation properties of photo-crosslinkable hydrogel can meet various requirements of the bone and cartilage scaffolds, which enable it to serve as an effective bio-ink for 3D bioprinting. Here, in this review, we first introduce commonly used photo-crosslinkable hydrogel materials and additives (such as nanomaterials, functional cells, and drugs/cytokine), and then discuss the applications of the 3D bioprinted photo-crosslinkable hydrogel scaffolds for bone and cartilage engineering. Finally, we conclude the review with future perspectives about the development of 3D bioprinting photo-crosslinkable hydrogels in bone and cartilage engineering.

45 citations

Journal ArticleDOI
TL;DR: In this paper , the pyramid evolution process of polyphenol-based hydrogels from crosslinking structures to derived properties and then to biomedical applications is elaborated, as well as the efficient reverse design considerations of these hydrogel systems are proposed.

44 citations

Journal ArticleDOI
TL;DR: In this article, a review has addressed the most recent advances in the tissue engineering of various organs with a focus on the applications of nanomaterials in this field, and the nature of damaged tissues, as well as scaffolds' composition, porous structure, degradability, and biocompatibility are determinant factors for successful tissue engineering.

38 citations