Author
Patricia F. Walker
Other affiliations: DuPont, Humboldt University of Berlin, HealthPartners ...read more
Bio: Patricia F. Walker is an academic researcher from University of Minnesota. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 22, co-authored 61 publications receiving 2089 citations. Previous affiliations of Patricia F. Walker include DuPont & Humboldt University of Berlin.
Topics: Medicine, Population, Internal medicine, Refugee, Cystic fibrosis
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors present characteristics and subgroup analyses from the first 1257 patients enrolled in the study, and conclude that there are no differences in outcomes of patients with short vs long latency of DILI.
576 citations
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Willamette University1, Novant Health2, Hackensack University Medical Center3, Sarah Cannon Research Institute4, University of Colorado Boulder5, Royal Bournemouth Hospital6, Universidade Federal do Rio Grande do Sul7, Tel Aviv Sourasky Medical Center8, University of Manitoba9, Stanford University10, Vita-Salute San Raffaele University11, Katholieke Universiteit Leuven12, Ohio State University13, University of Lyon14, University of Texas MD Anderson Cancer Center15, AstraZeneca16
TL;DR: The primary endpoint was progression-free survival between the two combination-therapy groups, assessed by independent review committee.
329 citations
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TL;DR: Immigrants who are visitors of friends and relatives in other countries account for a high volume of international travelers and are at markedly increased risk of travel-related illness.
Abstract: ContextIn the United States, 10% of the population was born outside of its
borders. Immigrants and their children frequently return to visit their homeland,
referred to as visiting friends and relatives (VFRs). They account for a disproportionately
high volume of international travel.Evidence AcquisitionSearches of MEDLINE, World Health Organization, Centers for Disease
Control and Prevention, International Society of Travel Medicine, and American
Society of Tropical Medicine computerized databases, conference proceedings
and abstracts, US Census Bureau, bibliographies of pertinent articles, and
travel medicine texts. Priority was given to recent (1996-2003) evidence,
addressing VFR travelers. General sources including travel medicine and immigrant
health were also used.Evidence SynthesisImmigrants visiting friends and relatives experience excessive rates
of travel-related morbidity and mortality. Lack of pretravel care is common
due to patient and clinician barriers to care, preexisting health beliefs,
and incomplete childhood vaccinations. Travel patterns increase risk with
VFRs traveling to high-risk destinations. Susceptibility to infectious and
noninfectious illnesses is often increased because of multiple preexisting
medical problems and extremes of age. Infectious diseases differ in etiology
and magnitude from those of traditional travelers. For example with malaria,
VFRs are frequently prescribed inappropriate prophylaxis or take none at all,
have longer stays, spend time in high-risk areas, and do not appropriately
adhere to chemoprophylaxis regimens. Effective pretravel health advice, guidelines,
and services for this high-risk population are essential. There are already
a number of useful and readily available databases that may aid clinicians
in providing optimal travel-related preventive and therapeutic care.ConclusionsImmigrants who are visitors of friends and relatives in other countries
account for a high volume of international travelers and are at markedly increased
risk of travel-related illness. New strategies are needed to properly address
the needs of VFR travelers. Pretravel services should be convenient, accessible,
affordable, culturally competent, and if possible, located within clinics
serving immigrant populations. Clinicians caring for VFRs should be knowledgeable
about their travel-related risks and have access to regularly updated, detailed
pretravel health information.
233 citations
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TL;DR: The current findings suggest that the severity and prevalence of hyperhidrosis are both higher than previously thought, indicating a need for greater awareness of the condition and its associated treatment options among medical professionals.
Abstract: Current published estimates of the prevalence of hyperhidrosis in the United States are outdated and underestimate the true prevalence of the condition. The objectives of this study are to provide an updated estimate of the prevalence of hyperhidrosis in the US population and to further assess the severity and impact of sweating on those affected by the condition. For the purposes of obtaining prevalence, a nationally representative sample of 8160 individuals were selected using an online panel, and information as to whether or not they experience hyperhidrosis was obtained. The 393 individuals (210 female, 244 non-Hispanic white, 27 black, mean age 40.3, SE 0.64) who indicated that they have hyperhidrosis were asked further questions, including body areas impacted, severity of symptoms, age of onset, and socioemotional impact of the condition. Current results estimate the prevalence of hyperhidrosis at 4.8 %, which represents approximately 15.3 million people in the United States. Of these, 70 % report severe excessive sweating in at least one body area. In spite of this, only 51 % have discussed their excessive sweating with a healthcare professional. The main reasons are a belief that hyperhidrosis is not a medical condition and that no treatment options exist. The current study’s findings with regard to age of onset and prevalence by body area generally align with the previous research. However, current findings suggest that the severity and prevalence are both higher than previously thought, indicating a need for greater awareness of the condition and its associated treatment options among medical professionals.
131 citations
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Harvard University1, Northwestern University2, Kaiser Permanente3, University of California, San Francisco4, Lehigh Valley Hospital5, Mount Sinai St. Luke's and Mount Sinai Roosevelt6, Albert Einstein College of Medicine7, University of California, San Diego8, Cornell University9, University of Southern California10, Mayo Clinic11, HealthPartners12, Emory University13, University of Washington14, Johns Hopkins University15, Tulane University16, University of Utah17, Centers for Disease Control and Prevention18
TL;DR: Data from Global TravEpiNet provide insight into the characteristics and pretravel healthcare of US international travelers who are at increased risk of travel-associated illness due to itinerary, purpose of travel, or existing medical conditions.
Abstract: Background International travel poses a risk of destination-specific illness and may contribute to the global spread of infectious diseases. Despite this, little is known about the health characteristics and pretravel healthcare of US international travelers, particularly those at higher risk of travel-associated illness. Methods We formed a national consortium (Global TravEpiNet) of 18 US clinics registered to administer yellow fever vaccination. We collected data regarding demographic and health characteristics, destinations, purpose of travel, and pretravel healthcare from 13235 international travelers who sought pretravel consultation at these sites from January 2009 through January 2011. Results The destinations and itineraries of Global TravEpiNet travelers differed from those of the overall population of US international travelers. The majority of Global TravEpiNet travelers were visiting low- or lower-middle-income countries, and Africa was the most frequently visited region. Seventy-five percent of travelers were visiting malaria-endemic countries, and 38% were visiting countries endemic for yellow fever. Fifty-nine percent of travelers reported ≥1 medical condition. Atovaquone/proguanil was the most commonly prescribed antimalarial drug, and most travelers received an antibiotic for self-treatment of travelers' diarrhea. Hepatitis A and typhoid were the most frequently administered vaccines. Conclusions Data from Global TravEpiNet provide insight into the characteristics and pretravel healthcare of US international travelers who are at increased risk of travel-associated illness due to itinerary, purpose of travel, or existing medical conditions. Improved understanding of this epidemiologically significant population may help target risk-reduction strategies and interventions to limit the spread of infections related to global travel.
126 citations
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TL;DR: Reading a book as this basics of qualitative research grounded theory procedures and techniques and other references can enrich your life quality.
13,415 citations
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TL;DR: The global prevalence of viral hepatitis remains high, while drug-induced liver injury continues to increase as a major cause of acute hepatitis.
1,799 citations
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TL;DR: In this article, the authors proposed a method to solve the problem of "no abstracts" and "no-no-expansions" in the context of artificial intelligence.
Abstract: No abstract provided.
1,471 citations
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TL;DR: Systematic inquiry into patients’ migration trajectory and subsequent follow-up on culturally appropriate indicators of social, vocational and family functioning over time will allow clinicians to recognize problems in adaptation and undertake mental health promotion, disease prevention or treatment interventions in a timely way.
Abstract: Background: Recognizing and appropriately treating mental health problems among new immigrants and refugees in primary care poses a challenge because of differences in language and culture and because of specific stressors associated with migration and resettlement. We aimed to identify risk factors and strategies in the approach to mental health assessment and to prevention and treatment of common mental health problems for immigrants in primary care. Methods: We searched and compiled literature on prevalence and risk factors for common mental health problems related to migration, the effect of cultural influences on health and illness, and clinical strategies to improve mental health care for immigrants and refugees. Publications were selected on the basis of relevance, use of recent data and quality in consultation with experts in immigrant and refugee mental health. Results: The migration trajectory can be divided into three components: premigration, migration and postmigration resettlement. Each phase is associated with specific risks and exposures. The prevalence of specific types of mental health problems is influenced by the nature of the migration experience, in terms of adversity experienced before, during and after resettlement. Specific challenges in migrant mental health include communication difficulties because of language and cultural differences; the effect of cultural shaping of symptoms and illness behaviour on diagnosis, coping and treatment; differences in family structure and process affecting adaptation, acculturation and intergenerational conflict; and aspects of acceptance by the receiving society that affect employment, social status and integration. These issues can be addressed through specific inquiry, the use of trained interpreters and culture brokers, meetings with families, and consultation with community organizations. Interpretation: Systematic inquiry into patients’ migration trajectory and subsequent follow-up on culturally appropriate indicators of social, vocational and family functioning over time will allow clinicians to recognize problems in adaptation and undertake mental health promotion, disease prevention or treatment interventions in a timely way.
999 citations
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TL;DR: This ACG Clinical Guideline is presented an evidence-based approach to diagnosis and management of DILI with special emphasis on DILi due to herbal and dietary supplements and DilI occurring in individuals with underlying liver disease.
630 citations