P
Patrick Chinestra
Researcher at French Institute of Health and Medical Research
Publications - 10
Citations - 162
Patrick Chinestra is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Long-term potentiation & Phage display. The author has an hindex of 7, co-authored 10 publications receiving 157 citations. Previous affiliations of Patrick Chinestra include Paul Sabatier University.
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Journal ArticleDOI
Alternative Initiation of Translation Accounts for a 67/45 kDa Dimorphism of the Human Estrogen Receptor ERα
TL;DR: This work suggests that this 45 kDa ERalpha form may originate from differential regulation of translation of the mRNA encoding the ERalpha, and demonstrates a mechanism of translation regulation that produced from a given mRNA either the wild type ER 67 kDa form or the AF1 deleted ER 45 k da isoform.
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Major differences between long-term potentiation and ACPD-induced slow onset potentiation in hippocampus
TL;DR: In contrast to long-term potentiation (LTP) induced by a tetanic train, SOP was accompanied by an increase in the magnitude of the presynaptic fiber volley, which suggests that the expression of SOP is due to a recruitment of additionalpresynaptic fibers by the test stimulus caused by the persistent block of K+ channels by ACPD.
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Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection
Marine Goffinet,Patrick Chinestra,Isabelle Lajoie-Mazenc,Claire Medale-Giamarchi,Gilles Favre,Jean-Charles Faye +5 more
TL;DR: The success of C1-N1N2 in discriminating activated Rho in immunofluorescence studies implies that this new tool, in collaboration with currently used RhoA and B antibodies, has the potential to analyze Rho activation in cell function and tumor development.
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NMDA redox site modulates long-term potentiation of NMDA but not of AMPA receptors
TL;DR: The induction of long-term potentiation mediated by NMDA receptors was prevented by a thiol oxidizing drug and restored by a disulfide reducing agent, while the induction of AMPA receptors was stopped by a reducing and an oxidizing agent.
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Detection of label-free cancer biomarkers using nickel nanoislands and quartz crystal microbalance
Adrian Martinez-Rivas,Patrick Chinestra,Gilles Favre,Sébastien Pinaud,Childérick Séverac,Jean-Charles Faye,Christophe Vieu +6 more
TL;DR: Ni nanoislands are used as an anchoring surface layer enabling the detection of a specific conformation of a protein, identified as a potential cancer biomarker, in a novel type of nanobiosensor to detect, at lower time consumption and with high sensitivity, specific biomolecules.