P
Patrick Giavalisco
Researcher at Max Planck Society
Publications - 144
Citations - 9476
Patrick Giavalisco is an academic researcher from Max Planck Society. The author has contributed to research in topics: Metabolomics & Gene. The author has an hindex of 46, co-authored 131 publications receiving 7412 citations.
Papers
More filters
Journal ArticleDOI
Intra- and interspecific variation in primate gene expression patterns
Wolfgang Enard,Philipp Khaitovich,Joachim Klose,Sebastian Zöllner,Florian Heissig,Patrick Giavalisco,Kay Nieselt-Struwe,Elaine A. Muchmore,Elaine A. Muchmore,Ajit Varki,Rivka Ravid,Gaby G. M. Doxiadis,Ronald E. Bontrop,Svante Pääbo +13 more
TL;DR: Three mouse species that are approximately as related to each other as are humans, chimpanzees, and orangutans are studied, and species-specific gene expression patterns indicating that changes in protein and gene expression have been particularly pronounced in the human brain are identified.
Journal ArticleDOI
Elemental formula annotation of polar and lipophilic metabolites using 13C, 15N and 34S isotope labelling, in combination with high-resolution mass spectrometry
Patrick Giavalisco,Yan Li,Annemarie Matthes,Aenne Eckhardt,Hans-Michael Hubberten,Holger Hesse,Shruthi Segu,Jan Hummel,Karin Köhl,Lothar Willmitzer +9 more
TL;DR: A comprehensive multi-isotope labelling-based strategy using fully labelled plant tissues, in combination with a fractionated metabolite extraction protocol, which can be applied in either an automated database-dependent or a database-independent analysis of the plant polar metabolome and lipidome.
Journal ArticleDOI
The sucrose–trehalose 6-phosphate (Tre6P) nexus: specificity and mechanisms of sucrose signalling by Tre6P
Umesh P Yadav,Alexander Ivakov,Regina Feil,Guangyou Duan,Dirk Walther,Patrick Giavalisco,Maria Piques,Petronia Carillo,Hans-Michael Hubberten,Mark Stitt,John E. Lunn +10 more
TL;DR: Trehalose-6-phosphate is a signal of sucrose status in plants and forms part of a homeostatic mechanism that maintains sucrose levels within a range that is appropriate for the cell type and stage of development.
Journal ArticleDOI
Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices
Saleh Alseekh,Asaph Aharoni,Yariv Brotman,Kévin Contrepois,John C. D’Auria,Jan Ewald,Jennifer C. Ewald,Paul D. Fraser,Patrick Giavalisco,Robert Hall,Matthias Heinemann,Hannes Link,Jie Luo,Steffen Neumann,Jens Nielsen,Leonardo Perez de Souza,Kazuki Saito,Uwe Sauer,Frank C. Schroeder,Stefan Schuster,Gary Siuzdak,Aleksandra Skirycz,Lloyd W. Sumner,Michael Snyder,Huiru Tang,Takayuki Tohge,Yulan Wang,Weiwei Wen,Si Wu,Guowang Xu,Nicola Zamboni,Alisdair R. Fernie +31 more
TL;DR: In this article, the authors present guidelines covering sample preparation, replication and randomization, quantification, recovery and recombination, ion suppression and peak misidentification, as a means to enable high-quality reporting of liquid chromatography and gas chromatography-mass spectrometry-derived data.
Journal ArticleDOI
Comprehensive Dissection of Spatiotemporal Metabolic Shifts in Primary, Secondary, and Lipid Metabolism during Developmental Senescence in Arabidopsis
Mutsumi Watanabe,Salma Balazadeh,Takayuki Tohge,Alexander Erban,Patrick Giavalisco,Joachim Kopka,Bernd Mueller-Roeber,Alisdair R. Fernie,Rainer Hoefgen +8 more
TL;DR: The metabolome data and the approach provided here can serve as a blueprint for the analysis of traits and conditions linking crop yield and senescence as well as provide clues to source-sink relations.